Enteric coated spheres produced by extrusion/spheronization provide effective gastric protection and efficient release of live therapeutic bacteria [PDF]
We present a novel but simple enteric coated sphere formulation containing probiotic bacteria (Lactobacillus casei). Oral delivery of live bacterial cells (LBC) requires live cells to survive firstly manufacturing processes and secondly GI microbicidal ...
Charalampopoulos, Dimitrios+4 more
core +1 more source
Erroneous formulation of delayed-release omeprazole capsules: alert for importing countries
Background Poor drug quality is a matter of serious concern, especially in countries where drug regulation and law enforcement are constrained by limited resources.
Mohammad Sofiqur Rahman+9 more
doaj +1 more source
Solid Lipid Nanoparticles for Duodenum Targeted Oral Delivery of Tilmicosin
Developing a targeted oral delivery system to improve the efficacy of veterinary antibiotics and reduce their consumption and environmental risks is urgent. To achieve the duodenum-targeted release of tilmicosin, the enteric granule containing tilmicosin-
Kaixiang Zhou+9 more
doaj +1 more source
Going Natural: Using polymers from nature for gastroresistant applications [PDF]
Nutraceuticals provide an additional health or medicinal benefit besides their nutritional value and are therefore marketed for the prevention and treatment of certain conditions.
Barbara Conway+3 more
core +1 more source
Regulating the pH of bicarbonate solutions without purging gases: Application to dissolution testing of enteric coated tablets, pellets and microparticles [PDF]
© 2020 Elsevier Ltd. All rights reserved. This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence http://creativecommons.org/licenses/by-nc-nd/4.0/.Dissolution media based on bicarbonate ...
Liu, Fang+5 more
core +1 more source
Wear-resistant thin films of MRI-230D-Mg alloy using plasma-driven electrolytic oxidation [PDF]
Wear resistant coatings were produced on a permanent mould cast MRI 230D Mg alloy by (a) PEO in silicate based electrolyte, (b) PEO in phosphate based electrolyte, (c) hybrid coatings of silicate PEO followed by laser surface alloying (LSA) with Al and Al2O3, and (d) hybrid coatings of phosphate PEO followed by LSA with Al and Al2O3.
arxiv +1 more source
Air Entrainment in Dynamic Wetting: Knudsen Effects and the Influence of Ambient Air Pressure [PDF]
Recent experiments on coating flows and liquid drop impact both demonstrate that wetting failures caused by air entrainment can be suppressed by reducing the ambient gas pressure. Here, it is shown that non-equilibrium effects in the gas can account for this behaviour, with ambient pressure reductions increasing the gas' mean free path and hence the ...
arxiv +1 more source
Active individual nanoresonators optimized for lasing and spasing operation [PDF]
Plasmonic nanoresonators consisting of a gold nanorod and a spherical silica-core and gold-shell, both coated by a gain layer, were optimized to maximize the near-field enhancement (NF-type) and far-field outcoupling (FF-type), and to enter into the spasing operation region (NF-c*-type).
arxiv
Enteric-Coated Cysteamine Bitartrate in Cystinosis Patients
Cystinosis is a severe inherited metabolic storage disease caused by the lysosomal accumulation of cystine. Lifelong therapy with the drug cysteamine bitartrate is necessary. Cysteamine cleaves intralysosomal cystine, and thereafter, it can exit from the organelle.
Klank, S. (Sabrina)+8 more
openaire +5 more sources
Enteric coating of ibuprofen tablets (200 mg) using an aqueous dispersion system [PDF]
Ibuprofen is a propionic acid derivative that belongs to the class NSAIDs. Major adverse reactions associated with Ibuprofen are related to GIT and include peptic and mucosal ulcers, dyspepsia, severe gastric pain and bleeding, that results in excessive ...
Aslam, Nousheen+4 more
core +4 more sources