Results 111 to 120 of about 1,591,463 (323)

Diagnostic host gene signature for distinguishing enteric fever from other febrile diseases

EMBO Molecular Medicine, 2019
Misdiagnosis of enteric fever is a major global health problem, resulting in patient mismanagement, antimicrobial misuse and inaccurate disease burden estimates.
Christoph J Blohmke, J. Muller, M. Gibani, H. Dobinson, S. Shrestha, S. Perinparajah, C. Jin, H. Hughes, L. Blackwell, S. Dongol, A. Karkey, F. Schreiber, D. Pickard, B. Basnyat, G. Dougan, S. Baker, A. Pollard, T. Darton   +17 more
semanticscholar   +1 more source

Appendicular mass – a rare form of tuberculosis [PDF]

, 2017
Tuberculosis is in the top 10 causes of death worldwide, being one of the most deadly infectious diseases. It is estimated that one of three people from the entire earth population has a latent infection with M tuberculosis.
Balalau, Cristian, Banu, Petrisor, Bratucu, Mircea, Constantin, Vlad D., Popa, Florian, Vladescu, Teodora   +5 more
core   +4 more sources

Parallel Genome‐Wide CRISPR Screens Reveal SORL1 and ZFYVE19 as Sequential Host Determinants of Salmonella Infection

Advanced Science, EarlyView.
To distinguish how Salmonella invades cells vs how it survives long‐term, a parallel CRISPR screening platform is developed. This approach reveals the host proteins that the bacterium exploits at different stages of infection. The study identifies SORL1 as a novel host factor for invasion and demonstrates that blocking it with an antibody effectively ...
Sehee Yun, Seoyeon Kim, Seonggyu Kim, Minsoo Noh, Dae‐Kyum Kim, Eun‐Jin Lee, Hunsang Lee   +6 more
wiley   +1 more source

Kathmandu, Nepal: Still an enteric fever capital of the world

Journal of Infection in Developing Countries, 2008
Kathmandu, the capital city of Nepal, has been previously coined an enteric fever capital of the world. Several studies have poignantly emphasized the significant burden of enteric fever within the local population and in travellers visiting the area ...
Abhilasha Karkey, Amit Aryjal, Buddha Basnyat, Stephen Baker   +3 more
doaj   +1 more source

An Engineered Solidified Peptide Hemocyte Sponge as Nanomotor Storage to Combat Bacterial Colitis

Advanced Science, EarlyView.
Peptides immobilized via nickel coordination can stabilize the framework structure. Following coating with red blood cell membranes, these constructs are capable of continuously sequestering endotoxins and mitigating colonic pathogenic damage by alleviating bacterial‐induced ferroptosis.
Yuxin Fang, Jianming Yan, Tongxin Yu, Zichuan An, Kaikai Lv, Chenyu Xue, Hongyang Yu, Na Dong, Anshan Shan   +8 more
wiley   +1 more source

Epidemiological Profile of Enteric Fever Cases Admitted In SCSMGH, Solapur

National Journal of Community Medicine, 2011
Enteric fever, though occurs in all parts of the world, is a serious public - health problem in developing countries. It is one of the important causes of morbidity in India due to high rates of complications and hospitalization.
Malangori A. Parande, C. G. Patil, Madhavi V Rayate, Mehboob U Lukde   +3 more
doaj  

Assessment and Translation of the Antibody-in-Lymphocyte Supernatant (ALS) Assay to Improve the Diagnosis of Enteric Fever in Two Controlled Human Infection Models and an Endemic Area of Nepal

Frontiers in Microbiology, 2017
New diagnostic tests for enteric fever are urgently needed to assist with timely antimicrobial treatment of patients and to measure the efficacy of prevention measures such as vaccination.
Thomas C. Darton, Thomas C. Darton, Thomas C. Darton, Claire Jones, Sabina Dongol, Merryn Voysey, Merryn Voysey, Christoph J. Blohmke, Rajendra Shrestha, Abhilasha Karkey, Abhilasha Karkey, Mila Shakya, Amit Arjyal, Claire S. Waddington, Malick Gibani, Michael J. Carter, Michael J. Carter, Buddha Basnyat, Stephen Baker, Andrew J. Pollard   +19 more
doaj   +1 more source

Clinical features of varicella-zoster virus infection [PDF]

, 2018
Varicella-zoster virus (VZV) is a pathogenic human herpes virus that causes varicella (chickenpox) as a primary infection, following which it becomes latent in peripheral ganglia.
Gershon, Anne A., Kennedy, Peter G.E.
core   +1 more source

Traceless Regulation of Genetic Circuitry

Advanced Science, EarlyView.
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley   +1 more source

Investigating Clinical and Biochemical Variances between Drug Resistant and Drug Susceptible Enteric Fever in Children [PDF]

Liaquat National Journal of Primary Care
Background: Two main types of resistance are observed in Salmonella Typhi (S. Typhi): Multi-Drug Resistant (MDR) and Extensively Drug-Resistant (XDR). The treatment of MDR typhoid fever often involves oral medication and intravenous therapy.
Shahina Hanif, Mohammad Hanif Memon, Farhan Saeed, Erum Saboohi, Farhat Ali, Marium Akram   +5 more
doaj   +1 more source