Results 241 to 250 of about 57,049 (308)

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner   +3 more
wiley   +1 more source

Ileal Perforation and Enteric Fever: Implications for Burden of Disease Estimation. [PDF]

open access: yesJ Infect Dis, 2021
Njarekkattuvalappil SK   +22 more
europepmc   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner   +7 more
wiley   +1 more source

A rare case report of enteric fever causing gallbladder perforation. [PDF]

open access: yesInt J Surg Case Rep, 2021
Bhandari TR, Khan SA, Jha JL, Sah JK.
europepmc   +1 more source

Impact of severe intra‐abdominal adhesions on early maternal complications following cesarean delivery

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The rising rates of cesarean delivery (CD), which are a leading cause of intra‐abdominal adhesions, represent a major concern for maternal health. We aimed to describe early maternal complications following CD in women with severe intra‐abdominal adhesions.
Shai Ram   +6 more
wiley   +1 more source

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