ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Adenovirus Disease and Ocular Symptoms in Children: Diagnosis and Prognostic Considerations
Adenoviral infections significantly impact pediatric health, manifesting as respiratory, gastrointestinal, and ocular disorders. We report a 14-year-old male with adenoviral pharyngoconjunctival fever (PCF) complicated by subconjunctival hemorrhage and ...
Jannatul Fardous +8 more
doaj +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
The associations between enteric pathogenic parasites and growth in infants in São Tomé were explored using a refined anthropometric approach to recognize early growth faltering.
M. Garzón +4 more
semanticscholar +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
The Gut Microbiome in Enteric Viral Infections: Underlying Mechanisms and Therapeutic Approaches
Despite growing recognition of the role of the gut microbiome in host health and in modulating pathogen activity, the dynamic and reciprocal relationship between enteric viruses and the gut microbial ecosystem remains insufficiently defined and requires ...
Alejandro Borrego-Ruiz, Juan J. Borrego
doaj +1 more source
Natural Secretory Immunoglobulins Promote Enteric Viral Infections
Enteric virus, such as norovirus, infections cause significant morbidity and mortality worldwide. However, direct antiviral infection prevention strategies are limited.
Holly Turula +13 more
semanticscholar +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Enteropathogen antibody dynamics and force of infection among children in low-resource settings. [PDF]
Little is known about enteropathogen seroepidemiology among children in low-resource settings. We measured serological IgG responses to eight enteropathogens (Giardia intestinalis, Cryptosporidium parvum, Entamoeba histolytica, Salmonella enterica ...
Arnold, Benjamin F +12 more
core
Heterogeneous Tfh cell populations that develop during enteric helminth infection predict the quality of type 2 protective response [PDF]
Aidil Zaini +13 more
openalex +1 more source

