Results 291 to 300 of about 861,731 (365)

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

Flow Cytometric Analysis and Sorting of Murine Enteric Nervous System Cells: An Optimized Protocol. [PDF]

Int J Mol Sci
Karkala F, de Bosscher I, Windster JD, Stroebel S, van Zanten L, Alves MM, Sacchetti A.   +6 more
europepmc   +1 more source

Enteric Nervous System: Neuropathic Gastrointestinal Motility [PDF]

Digestive Diseases and Sciences, 2016
openaire   +2 more sources

Remimazolam Ameliorates Autistic‐Like Behaviors via Suppression of Ferroptosis in VTA Dopaminergic Neurons in a Mouse Model of ASD

Advanced Science, EarlyView.
The ultra‐short‐acting sedative remimazolam has a sustained therapeutic effect on the core symptoms of VPA‐exposed mice. Remimazolam, a GABA agonist, exerts its therapeutic effects by protecting dopamine neurons in the VTA of VPA‐exposed mice. Meanwhile, ferroptosis is the critical mechanism by which remimazolam protects VTA dopaminergic neurons and ...
Yuxin Zhang, Jianwei Lin, Chaoyang Tong, Xin Fu, Mengqin Shan, Yue Huang, Kan Zhang, Jijian Zheng   +7 more
wiley   +1 more source

AI-powered 3D pathology protocol enhances enteric nervous system visualization and quantification for clinical diagnostics. [PDF]

Theranostics
Yun YH, Chung KY, Lee Y, Sung TS, Ko D, Ryoo SB, Kim HY, Park KJ, Im JP, Kim BG, Kim JS, Koh SJ, Choi HJ.   +12 more
europepmc   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Immune cell profiling reveals diverse niches of immune residents of the enteric nervous system and potential neuroimmune interactions. [PDF]

Proc Natl Acad Sci U S A
Wang H, Zaini A, Cardwell B, Rowe MC, Butler A, Wong CHY, Poole DP, Marsland B, Bornstein JC, Harris NL.   +9 more
europepmc   +1 more source

Mouse models of Hirschsprung disease and other developmental disorders of the enteric nervous system: Old and new players

, 2016
Nadège Bondurand, E. Michelle Southard‐Smith   +1 more
openalex   +2 more sources

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Microbiota-dependent Formylated Peptide Receptor (Fpr1/2) Signaling Regulates Enteric Nervous System Development and Gastrointestinal Motility in Mice. [PDF]

Cell Mol Gastroenterol Hepatol
Chandrasekharan B, Wu H, Smoller C, Kim J, Wolfarth AA, Eboka R, Boyer D, Metzger AJ, Addis CR, Liu K, Srinivasan S, Macpherson AJ, Jones RM, Neish AS.   +13 more
europepmc   +1 more source