Results 161 to 170 of about 364,513 (253)

Detection of enteric viruses in source and treated waters of the city of Hamadan, Iran. [PDF]

PeerJ
Ansari N, Mazaheri Z, Owliaee I, Abbaszadegan M, Alum A, Amini R, Beikpour F, Azizi Jalilian F.   +7 more
europepmc   +1 more source

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

Advanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer, Rong Zhu, Manuel Reithofer, Gerhard Stadlmayr, Katharina Stadlbauer, Panchika Prangkio, Christoph Rippel, Markus Hahn, Aniko Eva Kasztner, Stefanie Stohl, Petr Bednar, Daniel Ruzek, David Glück, Robert Tampé, Gordana Wozniak‐Knopp, Yoo Jin Oh, Miriam Klausberger, Peter Hinterdorfer   +17 more
wiley   +1 more source

Evaluation of false positive enteric viruses results from the BIOFIRE® FILMARRAY® gastrointestinal PCR panel. [PDF]

J Clin Virol
Chhabra P, Cates J, Bartlett E, Embury SA, Rizwan A, Williams FA, Kambhampati AK, Marconi VC, Epstein L, Jasarevic R, Kraft CS, Rodriguez-Barradas MC, Morones RG, Covarrubias MA, Beenhouwer DO, Goldin E, Brown ST, Pena I, Lucero-Obusan CA, Holodniy M, Gautam R, Mirza SA, Vinjé J, Surveillance Platform for Enteric and Respiratory Infectious Organisms at the VA (SUPERNOVA) AGE Surveillance Group.   +23 more
europepmc   +1 more source

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

Advanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang, Xiaowei Cai, Xiaoyan Zhong, Tian Qiu, Qinwei Lu, Jiahao Qin, Fei Gong, Yecheng Huang, Chenyu Jiang, Youdong Chen, Yuan Cheng, Liang Cheng   +11 more
wiley   +1 more source

Persistence of human enteric viruses in artificial and human saliva. [PDF]

PLoS One
Kosgei SC, Birch ON, Greaves JC.
europepmc   +1 more source

Loss of CYLD on Chromosome 16q Impairs Homologous Recombination and Genomic Stability Through TIRR Degradation

Advanced Science, EarlyView.
Chromosome 16q loss drives genomic instability through disruption of the CYLD–TIRR–53BP1 axis. CYLD preserves homologous recombination by stabilizing TIRR and limiting 53BP1 accumulation at DNA double‐strand breaks. CYLD deficiency redirects repair toward error‐prone non‐homologous end joining, promotes mutational burden and homologous recombination ...
Mingming Lu, Jialu Kang, Qi Ye, Zixi Wang, Lei Li, Yuzeshi Lei, Leihong Ye, Tianjie Liu, Bin Wang, Tao Liu, Shan Xu, Ke Wang, Yong Zhang, Jian Ma, Lei Li   +14 more
wiley   +1 more source

Prevalence and genetic diversity of enteric viruses in Sub-Saharan Africa: a systematic review and meta-analysis. [PDF]

BMC Infect Dis
Badjo AOR, Kabore NF, Zongo A, Agbadu J, Belarbi E, Ouedraogo AS.   +5 more
europepmc   +1 more source

Looking into sewage: how far can metagenomics help to detect human enteric viruses? [PDF]

Front Microbiol, 2023
Schaeffer J, Desdouits M, Besnard A, Le Guyader FS.   +3 more
europepmc   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

A sixteen-month monitoring of human enteric viruses associated with acute gastroenteritis in Senegal. [PDF]

Gut Pathog
Kébé O, Ba BS, Thiaw FD, Fall C, Barry MA, Boussiengui LG, Diallo JP, CoAg “diarrhées sanglantes” Investigators, Ndiaye N, Mamadou Ndiaye EH, Sall AA, Diop B, Dièye Y, Faye O, Faye M.   +14 more
europepmc   +1 more source