Results 71 to 80 of about 141,204 (370)
This study pioneers a rational nanozyme design strategy guided by electron transfer mechanisms while advancing biosensing paradigms through interpretable machine learning‐enhanced signal intelligence. By transforming biosensors from passive transducers to active diagnostic systems, this work establishes a versatile framework for addressing global ...
Yuechun Li+9 more
wiley +1 more source
Porcine sapoviruses, members of the family Caliciviridae, have been considered as an aetiological agent of gastroenteritis in pigs. In this study, we analysed 251 faecal samples obtained from 3 to 90 day-old diarrhoeic pigs in the Czech Republic between ...
L. Dufkova, P. Kulich, J. Prodelalova
doaj +1 more source
Once a poor village, Shenzhen is now one of the wealthiest cities in China. David Cyranoski learns its plans for the future.
openaire +3 more sources
KLK1 downregulation disrupts the intestinal mucosal barrier and impairs kallikrein‐kinin signaling, thereby reducing Lys‐des‐Arg9‐BK production. This enhances B1R activation on ADAMDEC1⁺ fibroblasts, promoting inflammation and extracellular matrix (ECM) remodeling. The resulting iCAFs promote colorectal cancer progression, highlighting a novel KLK1‐B1R
Lisha Zhou+14 more
wiley +1 more source
ABSTRACT Aim The prognostic immune nutritional index (PINI) is increasingly recognized for its potential clinical utility. However, multifaceted evaluations of its ability to predict oncological outcomes in colorectal cancer (CRC) and its association with postoperative infectious complications remain limited.
Shinji Yamashita+9 more
wiley +1 more source
The mycotoxin deoxynivalenol predisposes for the development of Clostridium perfringens-induced necrotic enteritis in broiler chickens [PDF]
Both mycotoxin contamination of feed and Clostridium perfringens-induced necrotic enteritis have an increasing global economic impact on poultry production. Especially the Fusarium mycotoxin deoxynivalenol (DON) is a common feed contaminant.
Antonissen, Gunther+13 more
core +10 more sources
Enzymes as Feed Additive to Aid in Responses Against Eimeria Species in Coccidia-Vaccinated Broilers Fed Corn-Soybean Meal Diets with Different Protein Levels [PDF]
This research aimed to evaluate the effects of adding a combination of exogenous enzymes to starter diets varying in protein content and fed to broilers vaccinated at day of hatch with live oocysts and then challenged with mixed Eimeria spp. Five hundred
Clack, Beatrice A.+8 more
core +2 more sources
Hierarchical Superposition Framework Reveals the Complex Effects of Natural Medicine Formulas
A novel hierarchical superposition pharmacological model incorporates the principle of hierarchical structures from physics to simulate the spatiotemporal dynamics of drug combinations, to elucidate the universal law underlying drug combination effects. By modeling cross‐level causal transmission and attenuation, it advances beyond traditional additive
Weifeng Liang+3 more
wiley +1 more source
Cryptosporidial enteritis has a rising incidence in the USA, mostly affecting immunocompromised individuals and children. It has a self-limiting course in healthy hosts.
Shivantha Amarnath+4 more
doaj +1 more source