Results 71 to 80 of about 94,987 (195)

A second open reading frame in human enterovirus determines viral replication in intestinal epithelial cells

Nature Communications, 2019
Human enteroviruses (HEVs) of the family Picornaviridae, which comprises non-enveloped RNA viruses, are ubiquitous worldwide. The majority of EV proteins are derived from viral polyproteins encoded by a single open reading frame (ORF).
Haoran Guo, Yan Li, Guanchen Liu, Yunhe Jiang, Siyu Shen, Ran Bi, Honglan Huang, T. Cheng, Chunxi Wang, Wei Wei   +9 more
semanticscholar   +1 more source

CORRELATION BETWEEN ENROVIRUS INFECTION AND ACUTE STROKE ON THE GROUND OF VIROLOGICAL, MOLECULAR GENETIC AND SEROLOGICAL METHODS OF DIAGNOSIS

Медична наука України, 2018
Relevance. Numerous virological studies prove the importance of enteroviruses in human somatic pathology. However, the etiopathogenetic role of enterovirus infection in patients with acute cerebrovascular disorder (GVMK) is not sufficiently highlighted.
N.G. Andriushkova, N.S. Turchina, V.V. Melnуk, L.V. Dolinchuk, V.A. Poniatovskyi, V.P. Shyrobokov   +5 more
doaj   +1 more source

Mechanical force sensing drives extrusion of Enterovirus A71-infected cells from colonic epithelial organoids [PDF]

, 2022
Jasmine Moshiri, Ailsa Craven, Sara Mixon, Manuel R. Amieva, Karla Kirkegaard   +4 more
openalex   +1 more source

Fluoxetine Inhibits Enterovirus Replication by Targeting the Viral 2C Protein in a Stereospecific Manner

ACS Infectious Diseases, 2019
Enteroviruses (family Picornaviridae) comprise a large group of human pathogens against which no licensed antiviral therapy exists. Drug-repurposing screens uncovered the FDA-approved drug fluoxetine as a replication inhibitor of enterovirus B and D ...
Lisa Bauer, Roberto Manganaro, Birgit Zonsics, J. Strating, Priscila El Kazzi, Moira Lorenzo Lopez, Rachel Ulferts, Clara van Hoey, M. Maté, T. Langer, B. Coutard, A. Brancale, F. V. van Kuppeveld   +12 more
semanticscholar   +1 more source

Origins of Enterovirus Replication Organelles Established by Whole-Cell Electron Microscopy

mBio, 2019
Enteroviruses are causative agents of a range of human diseases. The replication of these viruses within cells relies on specialized membranous structures termed replication organelles (ROs) that form during infection but whose origin remains elusive. To
C. Melia, C. Peddie, A. D. de Jong, E. Snijder, L. Collinson, A. Koster, H. M. van der Schaar, F. V. van Kuppeveld, M. Bárcena   +8 more
semanticscholar   +1 more source

Identification of Enterovirus C105 for the first time in New Zealand

Western Pacific Surveillance and Response, 2015
We report on the first identification of Enterovirus C105 (EV-C105) in New Zealand from a 52-year-old male hospitalized with mild respiratory tract symptoms.
Angela Todd, Susan Taylor, Q Sue Huang
doaj   +1 more source

Retrospective Genotyping of Enteroviruses Using a Diagnostic Nanopore Sequencing Workflow

Pathogens
Enteroviruses are among the most common viruses pathogenic to humans. They are associated with various forms of disease, ranging from mild respiratory illness to severe neurological diseases.
Vanessa van Ackeren, Stefan Schmutz, Ian Pichler, Gabriela Ziltener, Maryam Zaheri, Verena Kufner, Michael Huber   +6 more
doaj   +1 more source

Enterovirus Persistence in Cardiac Cells of Patients With Idiopathic Dilated Cardiomyopathy Is Linked to 5' Terminal Genomic RNA-Deleted Viral Populations With Viral-Encoded Proteinase Activities.

Circulation, 2019
BACKGROUND Group B enteroviruses are common causes of acute myocarditis, which can be a precursor of chronic myocarditis and dilated cardiomyopathy, leading causes of heart transplantation.
A. Bouin, P. Gretteau, Michel Wehbe, F. Renois, Y. N’Guyen, N. Lévêque, M. Vu, S. Tracy, N. Chapman, P. Bruneval, P. Fornés, B. Semler, L. Andréoletti   +12 more
semanticscholar   +1 more source

Twenty-nine Cases of Enterovirus-D68–associated Acute Flaccid Myelitis in Europe 2016

The Pediatric Infectious Disease Journal, 2018
Background: Enterovirus-D68 (EV-D68) is a respiratory virus within the genus Enterovirus and the family of Picornaviridae. Genetically, it is closely related to rhinovirus that replicates in the respiratory tract and causes respiratory disease.
M. Knoester, J. Helfferich, R. Poelman, C. V. Van Leer-Buter, O. Brouwer, H. Niesters   +5 more
semanticscholar   +1 more source

Ambulatory Pediatric Surveillance of Hand, Foot and Mouth Disease as Signal of an Outbreak of Coxsackievirus A6 Infections, France, 2014–2015

Emerging Infectious Diseases, 2016
The clinical impact of enteroviruses associated with hand, foot and mouth disease (HFMD) is unknown outside Asia, and the prevalence of enterovirus A71 (EV-A71) in particular might be underestimated. To investigate the prevalence of enterovirus serotypes
Audrey Mirand, François Vié le Sage, Bruno Pereira, Robert Cohen, Corinne Levy, Christine Archimbaud, Hélène Peigue-Lafeuille, Jean-Luc Bailly, Cécile Henquell   +8 more
doaj   +1 more source