Clinical perspectives of emerging pathogens in bleeding disorders. [PDF]
As a result of immunological and nucleic-acid screening of plasma donations for transfusion-transmissible viruses, and the incorporation of viral reduction processes during plasma fractionation, coagulation-factor concentrates (CFC) are now judged safe ...
Bozzette, Samuel +11 more
core +1 more source
Complete genome sequencing and analysis of six enterovirus 71 strains with different clinical phenotypes [PDF]
BACKGROUND: Hand, foot and mouth diseases (HFMD) caused by enterovirus 71(EV71) presents a broad spectrum of clinical manifestations ranging from mild febrile disease to fatal neurolocal disease. However, the mechanism of virulence is unknown.
Cheng-xi Sun +7 more
core +2 more sources
A new treatment for neurogenic inflammation caused by EV71 with CR2-targeted complement inhibitor [PDF]
BACKGROUND: Enterovirus 71 (EV71), one of the most important neurotropic EVs, has caused death and long-term neurological sequelae in hundreds of thousands of young children in the Asia-Pacific region in the past decade.
Carl Atkinson +18 more
core +1 more source
Modular nanosensing platforms utilize nanomaterials and functionalized interfaces to amplify trace different pathogens (like tuberculosis) antigen capture, suppress matrix interference, and enable multiplex detection. Their portability and cost‐effectiveness support rapid screening in resource‐limited settings and real‐time monitoring, advancing high ...
Mei Li +6 more
wiley +1 more source
Enterovirus 71, One Virus and Many Stories
Enterovirus 71 (EV71) has emerged as a significant cause of brainstem encephalitis and acute flaccid paralysis in Taiwan. It may be complicated by autonomic nervous system dysregulation and pulmonary edema (PE).
Shih-Min Wang +3 more
doaj +1 more source
Comparative analysis of viral shedding in pediatric and adult subjects with central nervous system-associated enterovirus infections from 2013 to 2015 in Switzerland. [PDF]
Several enterovirus (EV) genotypes can result in aseptic meningitis, but their routes of access to the central nervous system remain to be elucidated and may differ between the pediatric and adult populations.
Ambrosioni, J. +9 more
core +1 more source
Deteksi Penyebab Dan Sebaran Kasus Kejadian Luar Biasa Hand Foot and Mouth Diseases (HFMD) Tahun 2008-2012 [PDF]
Hand, foot, and mouth disease (HFMD) is a common disease caused by human enterovirus (HEV). The symptoms and signs of infection among children typically present with vesicular exanthema on the soles of their feet, the palms of their hands and in their ...
Herna, H. (Herna) +3 more
core
Neurovirulent enterovirus 71 (EV-A71) caused a massive epidemic in China in 2008–2011. While subgenotype C4 was the major causative agent, a few isolates were almost identical to the prototype EV-A71 strain and belonged to genotype A.
Yulia Vakulenko +2 more
doaj +1 more source
Development of novel miRNA-based vaccines and antivirals against Enterovirus 71 [PDF]
The Hand, Foot and Mouth Disease (HFMD) is caused by Enterovirus 71 (EV-A71) and Coxsackie viruses. Common HFMD symptoms are high fever (≥ 39oC), rashes, and ulcers but complications due to virulent EV-A71 may arise leading to cardiopulmonary failure and
Poh, Chit Laa *, Yee, Isabel Pin Tsin *
core
The Enterovirus 71 A-particle Forms a Gateway to Allow Genome Release: A CryoEM Study of Picornavirus Uncoating [PDF]
Since its discovery in 1969, enterovirus 71 (EV71) has emerged as a serious worldwide health threat. This human pathogen of the picornavirus family causes hand, foot, and mouth disease, and also has the capacity to invade the central nervous system to ...
AD Stuart +59 more
core +3 more sources

