N-terminal acetyltransferase 6 facilitates enterovirus 71 replication by regulating PI4KB expression and replication organelle biogenesis. [PDF]
Yang H +8 more
europepmc +1 more source
Corrigendum: Network pharmacology-based exploration identified the antiviral efficacy of Quercetin isolated from mulberry leaves against enterovirus 71 via the NF-κB signaling pathway. [PDF]
Liu T +9 more
europepmc +1 more source
Inferring B-cell derived T-cell receptor induced multi-epitope-based vaccine candidate against enterovirus 71: a reverse vaccinology approach. [PDF]
Swain SK +6 more
europepmc +1 more source
[Spermine suppresses GBP5-mediated NLRP3 inflammasome activation in macrophages to relieve vital organ injuries in neonatal mice with enterovirus 71 infection]. [PDF]
Tian Z +5 more
europepmc +1 more source
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Fatal enterovirus 71 encephalomyelitis
The Journal of Pediatrics, 1998During an outbreak of hand-foot-mouth disease caused by enterovirus 71 (EV-71) in 1997, 4 children presented with sudden cardiopulmonary collapse and minimal neurologic features. All children received cardiopulmonary resuscitation but died within a few hours of admission. Postmortem studies showed infection by EV-71 with extensive damage to the medulla
L C, Lum +9 more
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Update on enterovirus 71 infection
Current Opinion in Virology, 2014Human enterovirus type 71 (EV71) has emerged as a major cause of viral encephalitis in children worldwide. The identified EV71 receptors provide useful information for understanding EV71replication and tissue tropism. Host factors interact with the internal ribosome entry site (IRES) of EV71 to regulate viral translation.
Peng-Nien, Huang, Shin-Ru, Shih
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Although poliomyelitis has been eradicated from much of the globe, during the past 15 years countries in the Asia-Pacific region have been afflicted by large outbreaks of infection with the related human enterovirus A71 (EV71). This infection affects mostly children, causing hand-foot-and-mouth disease, aseptic meningitis, poliomyelitis-like acute ...
Mong How Ooi, Tom Solomon
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Enterovirus 71 meningoencephalitis complicating rituximab therapy
Journal of the Neurological Sciences, 2011We describe a fatal case of proven enterovirus 71 meningoencephalitis complicating monoclonal anti-CD20 antibody therapy for non-Hodgkin's lymphoma. B-cell depletion, an effective treatment strategy in an expanding spectrum of hematological and inflammatory disorders, impairs neutralising antibody-mediated clearance of enterovirus. The global threat of
Rebekah, Ahmed +6 more
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Enterovirus 71 (EV71) was first described in 1974 after it was isolated from patients in California (Schmidt et al., 1974) and has been associated with sporadic cases or outbreaks of a wide spectrum of diseases, including hand, foot, and mouth disease (HFMD), herpangina, aseptic meningitis, encephalitis, cerebellar ataxia, poliomyelitis-like syndrome ...
Luan-Yin Chang +3 more
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