Thermodynamic Data Remain a Hot Tip for Decoding Binding Affinity and Water Impact on Protein-Ligand Complex Formation to Assist Lead Optimization. [PDF]
J Med ChemKlebe G.
europepmc +1 more source
, 2007 The paper examines how metaphors play a key role in triggering individual emergence, involving the recognition of a new form, pattern, structure, organisation, model or concept, and then possible behaviour change. Individual emergence is thus of direct interest to the designer of learning systems.
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Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy
Advanced Science, EarlyView.A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang +7 more
wiley +1 more source
Efficient Prediction of Multicomponent Adsorption Isotherms and Enthalpies of Adsorption in MOFs Using Classical Density Functional Theory. [PDF]
J Phys Chem BThiele N +10 more
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Transforming Grain‐Boundary Brittle Precipitates to Ductility Pathways in Complex Concentrated Alloy
Advanced Science, EarlyView.By engineering graded BCC/L12 interfaces, brittle precipitates in a complex concentrated alloy enable sequential deformation, realizing gigapascal strength with >20% elongation to solve the strength‐ductility trade‐off. ABSTRACT Conventional wisdom holds that hard grain‐boundary (GB) precipitates embrittle structural alloys by acting as crack ...
Zhixin Li +14 more
wiley +1 more source
Verification of the General Applicability of a Predictive Model for the Physical Properties of Molten Salts in Heat Energy Storage Applications. [PDF]
ACS OmegaLi J, Shan J, Guo J.
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Advanced Science, EarlyView.This study shows that amyloid fibrils form nematic condensates via liquid–liquid crystalline phase separation (LLCPS). With increasing pH, this transition shifts toward disordered condensates formed through liquid–liquid phase separation (LLPS), in which birefringence with lack of a coherent nematic field symmetry originates from enthalpic fibril ...
Milad Radiom, Raffaele Mezzenga
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Enhancing Room-Temperature Hydrogen Storage Properties in Ti-V-Cr-Nb-Mo/Fe Multielement Alloys via Substitutional Tuning. [PDF]
ACS OmegaRahmouni MEH +6 more
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Advanced Science, EarlyView.A femtosecond UV pump–probe microscope resolves binding‐induced changes in protein excited‐state dynamics and converts these intrinsic contrasts into an equilibrium affinity readout. By probing tryptophan responses directly in solution, the approach enables quantitative determination of dissociation constants without labeling or immobilization ...
Jianghao Shen +5 more
wiley +1 more source
Studied on the kinetics of austenitizing phase transition of 1Cr13 steel
MetalurgijaThe austenitizing of steel plays an important role in improving its properties. Studying the kinetics of austenitizing of steel has certain theoretical significance for practical production. In this article, the Differential scanning calorimetry(DSC) was
L. Xue +4 more
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