Results 91 to 100 of about 5,878 (252)

Musculoskeletal Diseases: Mechanisms and Therapeutic Advances

MedComm, Volume 6, Issue 12, December 2025.
Musculoskeletal diseases comprise a broad spectrum of inflammatory, degenerative, and neoplastic disorders. Increasing evidence highlights the central role of immune regulation in their pathogenesis, with complex interactions among immune, bone, muscle, and stromal cells.
Xiao Ma, Eloy Yinwang, Xupeng Chai, Fangqian Wang, Zehao Chen, Shengdong Wang, Hao Zhou, Yucheng Xue, Jiangchu Lei, Fanglu Chen, Hengyuan Li, Shixin Chen, Shenzhi Zhao, Kelei Wang, Liang Chen, Junjie Gao, Zhaoming Ye, Nong Lin   +17 more
wiley   +1 more source

Pathogenicity of Misfolded and Dimeric HLA-B27 Molecules [PDF]

, 2011
The association between HLA-B27 and the group of autoimmune inflammatory arthritic diseases, the spondyloarthropathies (SpAs) which include ankylosing spondylitis (AS) and Reactive Arthritis (ReA), has been well established and remains the strongest ...
Antoniou, AN, Guiliano, DB, Lenart, I
core   +4 more sources

Static and Dynamic Balance Is Impaired in Patients With Long‐Term, Well‐Controlled Acromegaly: A Cross‐Sectional Study

Clinical Endocrinology, Volume 103, Issue 5, Page 703-710, November 2025.
ABSTRACT Objective Balance impairment is an underrecognized complication of acromegaly with potentially serious consequences for affected patients. In this study, we aimed to assess the balance in patients with long‐term acromegaly compared to non‐acromegalic controls. Design Cross‐sectional study.
Christian Rosendal, Annika Vestergaard Kvist, Rogério Pessoto Hirata, Peter Vestergaard, Jakob Dal   +4 more
wiley   +1 more source

The prevalence of axial spondyloarthritis in the UK: a cross-sectional cohort study [PDF]

, 2015
Background: Accurate prevalence data are important when interpreting diagnostic tests and planning for the health needs of a population, yet no such data exist for axial spondyloarthritis (axSpA) in the UK.
Alex Macgregor, Andoni Toms, CH Roux, D Poddubnyy, E Collantes, E Tomero, Edward Pinch, F Costantino, J Sieper, JH Kellgren, JS Lawrence, Karl Gaffney, L Hamilton, L Hamilton, L Hoeven Van, Louise Hamilton, M Dougados, M Rojas-Vargas, M Rudwaleit, MR Underwood, R Angelis De, S Linden Van der, SZ Aydin, Victoria Warmington, W Mau   +24 more
core   +1 more source

Impact of diclofenac risk minimization measures addressing cardiovascular risk on analgesic use in musculoskeletal disorders

British Journal of Clinical Pharmacology, Volume 91, Issue 10, Page 2998-3008, October 2025.
Aims In 2013, risk minimization measures (RMMs) were introduced in Europe to address the increased cardiovascular risk linked to diclofenac. This study aimed to assess the impact of those RMMs on analgesic use. Methods Primary care data from CPRD GOLD (UK) were used.
Tomas Lasys, Yared Santa‐Ana‐Tellez, Satu J. Siiskonen, Daniala L. Weir, Rolf H. H. Groenwold, Helga Gardarsdottir   +5 more
wiley   +1 more source

The use of intra-articular aneshesia as a diagnostic tool in canine lameness [PDF]

, 2012
Lameness in dogs may be difficult to localize because of mild pathologic changes or inconclusive clinical findings. Intra-articular anesthesia is proposed as a diagnostic method to localize the source of lameness.
Mosselmans, Lynn, Samoy, Yves, Van Ryssen, Bernadette, Van Vynckt, Delphine, Verhoeven, Geert, Verschooten, Francis   +5 more
core   +1 more source

Bone oedema‐like lesions at the enthesis of DIPJ collateral ligaments: MRI findings, management and outcome

Equine Veterinary Education, Volume 37, Issue 10, Page e242-e247, October 2025.
Summary Bone oedema‐like lesion is characterised by hyperintense signal in short tau inversion recovery (STIR) sequences on magnetic resonance imaging (MRI). Bone oedema‐like lesions involving the enthesis of the collateral ligament (CL) of the distal interphalangeal joint (DIPJ) have not been investigated as a cause of lameness.
F. Cavallier, F. Cantatore, M. Marcatili, M. Biggi   +3 more
wiley   +1 more source

Clinical Examination, Ultrasound and MRI Imaging of The Painful Elbow in Psoriatic Arthritis and Rheumatoid Arthritis: Which is Better, Ultrasound or MR, for Imaging Enthesitis? [PDF]

, 2017
Introduction: The purpose of the current study was to examine the painful elbow, and in particular enthesitis, in psoriatic arthritis (PsA) and rheumatoid arthritis (RA) using clinical examination, ultrasonography (US) and magnetic resonance imaging (MRI)
B Frediani, D Levin, D McGonagle, DD Gladman, EM Hay, F McQueen, H Marzo-Ortega, I Eshed, L Terslev, MA D’Agostino, P Balint, P Healy, PS Helliwell, S Aydin, WJ Taylor   +14 more
core   +1 more source

Diagnostic imaging findings and management of osteoarthritis in pigs with image‐guided intra‐articular injections

Veterinary Surgery, Volume 54, Issue 7, Page 1433-1442, October 2025.
Abstract Objective To describe the clinical and diagnostic imaging findings of pet pigs with osteoarthritis and determine the efficacy of intra‐articular (IA) injections in managing lameness. Study design Retrospective observational study. Animals A total of 16 pet pigs diagnosed with osteoarthritis and treated with non‐steroidal medications and IA ...
Reed H. Schultz, Jan F. Hawkins, Jesus A. Hermida   +2 more
wiley   +1 more source

Comparison of the effectiveness of low-energy laser treatment and sonotherapy in the healing of plantar aponeurosis enthesopathy symptoms

Journal of Education, Health and Sport, 2018
The aim of this study is to compare the effectiveness of healing using low-energy laser treatment and sonotherapy in the treatment of plantar aponeurosis enthesopathy symptoms.
Agata Bloch, Kinga Misiak, Łukasz Nowicki, Anna Złotnik, Krystian Kałużny, Anna Kałużna, Magdalena Hagner-Derengowska, Walery Zukow   +7 more
doaj   +3 more sources