Results 171 to 180 of about 181,249 (295)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

GUEST EDITORS’ NOTE

open access: yesPsychological Topics
Throughout history, our capacity to shed tears has attracted the attention of poets, writers, philosophers, and scholars. Moreover, humans' fascination with tears is evident in the significant roles they played in legends and myths. The main issues were
Asmir Gračanin   +2 more
doaj  

The cognitive connectome of men and women: a study on sex differences across three cohorts. [PDF]

open access: yesBiol Sex Differ
Gasparre D   +10 more
europepmc   +1 more source

A STUDY ON THE SPACE OF ENTIRE FUNCTIONS OF SEVERAL COMPLEX VARIABLES

open access: yesA STUDY ON THE SPACE OF ENTIRE FUNCTIONS OF SEVERAL COMPLEX VARIABLES
application ...
openaire  

Proximate Growth and Best Approximation in Lp-norm of Entire Functions

open access: yes
Let 0 be less than p less than infinity and Vg be the supremum of the absolute value of P in Pd, where Pd is the set of polynomials of degree less than d, and the norm of P on K is less than or equal to 1. Here, K is an L-regular compact set.
Harfaoui, Mohammed
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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