Results 151 to 160 of about 141,979 (204)

Pathways to productivity: how functional ecosystem service flow determines crop yield in prairie landscape. [PDF]

Landsc Ecol
Pashanejad E, Robinson BE, Parrott L.
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Rapid and Non-Destructive Detection of Moisture Content in Dried Areca Nuts Based on Near-Infrared Spectroscopy Combined with Machine Learning. [PDF]

Foods
Dai J, Wang S, Gan X, Wang Y, Dai W, Kang X, Su LY.   +6 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

A framework for reproducibly managing coupled research software and data assets based on shared transformation functions. [PDF]

Patterns (N Y)
Kuckertz P, Fuchs B, Schönau J, Gardian H, Knosala K, Arellano Ruiz ES, Göpfert J, Gils HC, Weinand JM, Jochem P, Linßen J, Stolten D.   +11 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Enhanced Philoponella Prominens Optimization (EESPPO) Algorithm Integrated with Experience Exchange Strategy for Global Optimization and Engineering Design Problems. [PDF]

Biomimetics (Basel)
Yan Z, Yu Y, Cao Y, Gao J.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Regional forest stock volume mapping using GEDI-based interpolation, multi-source remote sensing, and a multi-level stacking ensemble model in complex terrain. [PDF]

Front Plant Sci
Li Z, Shu Q, Fu L, Wei R, Zhang Y, Zhang X, Meng S.   +6 more
europepmc   +1 more source