Results 251 to 260 of about 900,353 (303)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Donor Bladder Inclusion in Kidney Transplantation: A Review of the Literature and our Clinical Experience. [PDF]

open access: yesCurr Urol Rep
Ciancio G   +8 more
europepmc   +1 more source

Millimeter-Scale Dual-Opposing RNA-Gradient Hydrogel for Interfacial Gene Silencing. [PDF]

open access: yesAdv Sci (Weinh)
Hoffman T   +11 more
europepmc   +1 more source

Actor Placement Optimization in WSANs by the PSO-HC-DGA Hybrid System for Two-Zone Industrial Environments. [PDF]

open access: yesSensors (Basel)
Kraikritayakul P   +5 more
europepmc   +1 more source

Evaluation of combined root exudate and rhizosphere microbiota sampling approaches to elucidate plant-soil-microbe interactions. [PDF]

open access: yesNew Phytol
Escudero-Martinez C   +15 more
europepmc   +1 more source

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