Results 61 to 70 of about 1,101,646 (327)
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Entire solutions of nonhomogenous differential equations
Journal of Mathematical Analysis and Applications, 1991 AbstractIn this paper, entire solutions of nonhomogenous differential equations of second order with polynomial coefficients in complex domain are considered. Bounds on the type and maximum modulus are obtained. Conditions for a solution to be entire and univalent are also given.
openaire +2 more sources
Entire solutions of Donaldson's equation [PDF]
arXiv, 2010 In this short note we shall construct infinite many nontrivial entire solutions to Donaldson's equation. We shall also prove a Liouville type theorem for entire solutions of the Donaldson equation. We believe that one should be able to classify all entire solutions of the Donaldson equation.
arxiv
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
A Bernstein result and counterexample for entire solutions to Donaldson's equation [PDF]
arXiv, 2015 We show that convex entire solutions to Donaldson's equation are quadratic, using a result of Weiyong He. We also exhibit entire solutions to the Donaldson equation that are not of the form discussed by He. In the process we discover some non-trivial entire solutions to complex Monge-Amp\`{e}re equations.
arxiv
The existence of solutions to certain type of nonlinear difference-differential equations
Open Mathematics, 2018 In this paper we study the entire solutions to a certain type of difference-differential equations. We also give an affirmative answer to the conjecture of Zhang et al.
Lü Weiran +3 more
doaj +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
The Keller–Osserman-type conditions for the study of a semilinear elliptic system
Boundary Value Problems, 2019 We study the following system of equations: 0.1 {Δu1=p1(|x|)f1(u1,u2)in RN,Δu2=p2(|x|)f2(u1,u2)in RN. $$ \textstyle\begin{cases} \Delta u_{1}=p_{1} ( \vert x \vert ) f_{1} ( u_{1},u_{2} ) &\text{in }\mathbb{R}^{N}, \\ \Delta u_{2}=p_{2} ( \vert x \vert )
Dragos-Patru Covei
doaj +1 more source