Results 121 to 130 of about 4,397,166 (245)
On the Entire Solutions of a Class of Differential Equations Related to Fermat-Type Equations
We study a substantially generalized version of the equation on nonlinear monomial differential equations, and obtain two-sided inequalities for the growth of entire solutions.
Liangwen Liao, Gengchen Wang
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Entire solutions for a two-component competition system in a lattice
, 2010 We study entire solutions of a two-component competition system with Lotka-Volterra type nonlinearity in a lattice. It is known that this system has traveling wave front solutions and enjoys comparison principle.
Guo, Jong-Shenq, Wu, Chang-Hong
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Entire solutions of semilinear elliptic equations / A. L. Gladkov, N. Slepchenkov
, 2004 We consider existence of entire solutions of a semilinear elliptic equation Δu = k(x)f(u) for x ∈ ℝn, n ≥ 3. Conditions of the existence of entire solutions have been obtained by different authors.
Slepchenkov, N., Gladkov, A.L.
core
Entire functions related to stationary solutions of the Kawahara equation
Electronic Journal of Differential Equations, 2016 In this study, we characterize the lengths of intervals for which the linear Kawahara equation has a non-trivial solution, whose energy is stationary. This gives rise to a family of complex functions.
Andre Luiz C. dos Santos +2 more
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source