Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Quasilinear problems with two parameters including superlinear and gradient terms
Electronic Journal of Differential Equations, 2014 In this article, we establish conditions for the existence of solutions for a quasilinear elliptic two-parameter problem with dependence on the gradient term in smooth bounded domains or in the whole space R^N.
Manuela C. Rezende, Carlos A. Santos
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Semi-Supervised Novelty Detection Using SVM Entire Solution Path
, 2013 Frank de Morsier +4 more
openalex +2 more sources
Some further results on the zeros and growths of entire solutions of second order linear differential equations [PDF]
, 1999 Zong-Xuan Chen, Chung-Chun Yang
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Entire Solutions in Lattice Delayed Differential Equations with Nonlocal Interaction: Bistable Cases [PDF]
, 2013 Z.-C. Wang, Wan‐Tong Li, Shigui Ruan
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ENTIRE SOLUTIONS OF HESSIAN EQUATIONS
, 2009 We study in this thesis the existence and uniqueness of entire solutions, in appropriate weighted Hölder spaces, of elliptic Hessian equations in Rn and Cn, with rotational invariance.
openaire +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Growth of entire solutions of algebraic differential equations
Electronic Journal of Differential Equations, 2012 In this article, by means of the normal family theory, we estimate the growth order of entire solutions of some algebraic differential equations and extend the result by Qi et al [14]. We also give some examples to show that our results occur in some
Wenjun Yuan, Yezhou Li, Jianming Lin
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