Results 211 to 220 of about 4,397,166 (245)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Fractional caputo modeling of delayed disease dynamics: sensitivity analysis and control strategies incorporating environmental influences. [PDF]
Sci RepPathak S, Kota VR.
europepmc +1 more source
Modern Solvation Thermodynamics from Macroscopic to Microscopic Approach. [PDF]
Entropy (Basel)Ben-Naim A.
europepmc +1 more source
Generating solutions for charged compact configurations in f(R) gravity. [PDF]
PLoS OneNoureen I, Mardan SA, Zahra A, Anwar I.
europepmc +1 more source
Whole-slide imaging in hematopathology: Current state, challenges and future opportunities. [PDF]
J Pathol InformNorouziani R +3 more
europepmc +1 more source