Results 31 to 40 of about 92,161 (217)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Chinese open information extraction based on DBMCSS in the field of national information resources
Open Physics, 2018 Binary entity relationship tuples can be applied in many fields such as knowledge base construction, data mining, pattern extraction, and so on. The purpose of entity relationship mining is discovering and identifying the semantic relationship.
Gan Jianhou +3 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Entity Resolution Based on Probabilistic Soft Logic Model [PDF]
Jisuanji gongcheng, 2017 As any closed atom adopts hard constraints in Entity Resolution(ER) algorithm based on Markov Logic Network(MLN),the reasoning and weight learning processes of the algorithm hardly converge to the optimal solution,which decreases the efficiency and ...
GONG Yunbao,GAN Liang,HUANG Jiuming
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Joint extraction model of entity relations based on decomposition strategy
Scientific ReportsNamed entity recognition and relation extraction are two important fundamental tasks in natural language processing. The joint entity-relationship extraction model based on parameter sharing can effectively reduce the impact of cascading errors on model ...
Ran Li +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Building a Spatial Database for Romanian Archaeological Sites [PDF]
Database Systems Journal, 2011 Spatial databases are a new technology in the database systems which allow storing, retrieving and maintaining geospatial data. This paper describes the steps which we have followed to model, design and develop a spatial database for Romanian ...
Aura-Mihaela MOCANU, Manole VELICANU
doaj
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Multi-Feature Fusion Event Argument Entity Recognition Method for Industrial Robot Fault Diagnosis
Applied Sciences, 2022 The advance of knowledge graphs can bring tangible benefits to the fault detection of industrial robots. However, the construction of the KG for industrial robot fault detection is still in its infancy.
Senye Chen +3 more
doaj +1 more source