Results 151 to 160 of about 387,911 (299)

The Skull beneath the Skin: Entity-Relationship Models of Information Artefacts

, 1996
Data modelling reveals the internal structure of an information system, abstracting away from details of the physical representation. We show that entity-relationship modelling, a well-tried example of a data-modelling technique, can be applied to both
D. R. Benyon, T. R. G. Green
core  

Aptamer‐Targeted PrPC Drives Colorectal Cancer Metastasis via a LYN‐STAT3 Complex and Enables Liquid Biopsy Detection

Advanced Science, EarlyView.
The aptamer WHY‐3E identifies PrPC as a CRC driver. Stabilized by USP18, endocytosed PrPC forms a LYN/STAT3 complex, upregulating MSN transcription to promote metastasis. Crucially, WHY‐3E sensitively detects PrPC‐positive circulating exosomes, establishing a robust theoretical foundation for non‐invasive clinical diagnostics.
Chunlin Wang, Hongyu Wu, Chaojing Zheng, Hao Zhang, Xiaoqiu Wu, Jiaqi Wang, Zewen Chang, Jun Xiang, Yunxiao Liu, Chenkai Zhang, Yuliuming Wang, Hao Jiang, Yuchen Zhong, Jun Luo, Ying Chen, NaNa Zhang, Weiyuan Zhang, Ziming Yuan, ChaoXia Zou, Weihong Tan, Meng Wang, Hanqing Hu, Tao Bing, Guiyu Wang   +23 more
wiley   +1 more source

Structured knowledge representation of the South China Sea: An LLM-based knowledge graph approach. [PDF]

PLoS One
Zhao R, Han Z, Liu H.
europepmc   +1 more source

Topology‐Aware Deep Learning on Higher‐Order Structures for Drug Response Prediction

Advanced Science, EarlyView.
We present TopDr, a topology‐aware deep learning framework that encodes both drugs and cell lines as multiscale simplicial complexes, capturing interactions at the 0‐, 1‐, and 2‐simplex levels. By jointly integrating local higher‐order neighborhoods and global topological structures, TopDr generates enriched representations for sensitivity prediction ...
Cong Shen, Guancen Lin, Chuan‐Shen Hu, Yong Wang   +3 more
wiley   +1 more source

A practical and nuanced framework for entity linking evaluation. [PDF]

J Biomed Semantics
Xu F, Nenadic G, Stevens R.
europepmc   +1 more source

A Multimodal Magnetically Driven Soft Robot With Integrated Actuation‐Sensing Based on Photothermal Reprogramming Technology

Advanced Science, EarlyView.
This work reports a thermally safe, photothermally reprogrammable magnetic soft robot with its reprogramming temperature tuned to ∼39.5°C for biocompatibility. It achieves multimodal locomotion (max speed of 1.8 BL/s) and integrates liquid‐metal capacitive sensing to monitor self‐motion and detect environmental changes in simulated gastric environments,
Liu Yang, Yuliao Dong, Kangning Li, Cheng Jing, Ben Wang, Lin Xu   +5 more
wiley   +1 more source

Proposal of a procedure to stratify the reidentification risk of medical data: RIMEDA. [PDF]

BMC Med Inform Decis Mak
Behre S, Kesztyüs D, Schnabel S, Kesztyüs T.   +3 more
europepmc   +1 more source

A Calculus for Fuzzy Queries on Fuzzy Entity-Relationship Model

, 2007
Most query languages are designed to retrieve information from databases containing precise and certain data using precisely specified commands. Application of fuzzy set theory to relational data models has been studied extensively in recent years.
Dr. Narasimha Bolloju
core  

How Advanced Artificial Intelligence Technologies Shape Drug–Drug and Drug–Target Interaction Modeling

Advanced Science, EarlyView.
This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley   +1 more source

Mapping the terminology of the early rescue chain to the Foundation of ICD-11: Registered report protocol. [PDF]

PLoS One
Tegegne MD, Tu SW, Ibrahim I, Cornet R, Niakan Kalhori SR, Deserno TM.   +5 more
europepmc   +1 more source