Results 111 to 120 of about 373,524 (318)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Linking entities through an ontology using word embeddings and syntactic re-ranking

BMC Bioinformatics, 2019
Background Although there is an enormous number of textual resources in the biomedical domain, currently, manually curated resources cover only a small part of the existing knowledge.
İlknur Karadeniz, Arzucan Özgür
doaj   +1 more source

Improving Biomedical Entity Linking with Retrieval-enhanced Learning [PDF]

, 2023
Zhenxi Lin, Ziheng Zhang, Xian Wu, Yefeng Zheng   +3 more
openalex   +1 more source

Liquid Crystalline Inverted Lipid Phases and Reverse Micelles in Drug Delivery: From Molecular Design to Therapeutic Potential

Advanced Functional Materials, EarlyView.
Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu, Mulazim Hussain Asim, Soheil Haddadzadegan, Andreas Bernkop‐Schnürch   +3 more
wiley   +1 more source

EREL: an Entity Recognition and Linking algorithm

Journal of Information and Telecommunication, 2018
This paper introduces the EREL algorithm that integrates Entity Recognition, Co-reference Resolution (CR) and Disambiguation. The algorithm recognizes entity mentions as the longest name based on the name dictionary constructed from the Wikipedia data ...
Cuong Duc Nguyen, Trong Hai Duong
doaj   +1 more source

A Programmable Semiconductor Containing Active Molecular Photoswitches Located in the Crystal's Volume Phase

Advanced Functional Materials, EarlyView.
A novel approach for the design of functional semiconductors is presented, which utilizes the excellent optoelectronic properties of layered hybrid perovskites and the possibility to introduce a molecular photoswitch as the organic spacer. This concept is successfully demonstrated on a coumarin‐based system with the possibility to change the bandgap ...
Oliver Treske, Yaşar Krysiak, Hans Tornatzky, Markus R. Wagner, Sebastian Polarz   +4 more
wiley   +1 more source

Simple Hierarchical Multi-Task Neural End-To-End Entity Linking for Biomedical Text [PDF]

, 2020
Maciej Wiatrak, Juha Iso-Sipilä
openalex   +1 more source

Evaluating Pretrained Transformer Models for Entity Linking in Task-Oriented Dialog [PDF]

, 2021
Sai Muralidhar Jayanthi, Varsha Embar, Karthik Raghunathan   +2 more
openalex   +1 more source

BioKGrapher: Initial evaluation of automated knowledge graph construction from biomedical literature

Computational and Structural Biotechnology Journal
Background The growth of biomedical literature presents challenges in extracting and structuring knowledge. Knowledge Graphs (KGs) offer a solution by representing relationships between biomedical entities.
Henning Schäfer, Ahmad Idrissi-Yaghir, Kamyar Arzideh, Hendrik Damm, Tabea M.G. Pakull, Cynthia S. Schmidt, Mikel Bahn, Georg Lodde, Elisabeth Livingstone, Dirk Schadendorf, Felix Nensa, Peter A. Horn, Christoph M. Friedrich   +12 more
doaj   +1 more source

An Ultrafast Self‐Gelling Versatile Hydrogel for Rapid Infected Burn Wound Repair in Military Medicine

Advanced Functional Materials, EarlyView.
A self‐gelling PG@PAC (POD/Gel‐CDH@PA/CHX) powder is developed for infected burn care in austere settings. Upon contact with wound exudate, it instantly forms an adhesive hydrogel, providing simultaneous hemostasis, broad‐spectrum antibacterial activity, reactive oxygen species scavenging, and immunomodulation. In a murine model of S.
Liping Zhang, Zhangrui Wu, Xiansheng Zhao, Geng Wang, Quyang Yang, Minxia zhang, Xiaowei Wang, Xiujun Cheng, Changyue Wu, Dan Wu, Yutian Yang, Canbin Dong, Tao Zhang, Weiqiang Tan, Ningwen Zhu   +14 more
wiley   +1 more source