Results 221 to 230 of about 3,610,484 (281)

PharmVar GeneFocus: NAT2—Genetic Variation and Updated Nomenclature

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human N‐acetyltransferase 2 (NAT2) gene. NAT2 metabolizes several clinically used drugs including isoniazid, hydralazine, amifampridine, procainamide, and sulfonamides such as dapsone, and also some highly carcinogenic arylamines.
Georgia Papanikolaou   +14 more
wiley   +1 more source

The Stroke Riskometer™ in the Outpatient Clinic as an Educational Campaign for Acute Ischemic Stroke. [PDF]

open access: yesRev Neurol
Ortega-Moreno DA   +7 more
europepmc   +1 more source

Pharmacogenomics of Major Depressive Disorder in Indigenous Amazonian Populations

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Major depressive disorder is a highly prevalent psychological disorder worldwide and its main treatment is the use of Selective Serotonin Reuptake Inhibitors. However, few studies have demonstrated the relationship between the presence of genetic variants in pharmacogenes and the efficacy of these drugs, especially in populations with a unique genetic ...
Kaio Evandro Cardoso Aguiar   +9 more
wiley   +1 more source

Environmental health literacy among riverside residents in the Amazon region of Pará. [PDF]

open access: yesRev Esc Enferm USP
Andrade ÉFR   +8 more
europepmc   +1 more source

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Thiopurine Dosing Based on TPMT and NUDT15 Genotypes: 2025 Update

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Thiopurine methyltransferase (TPMT) and Nudix hydrolase 15 (NUDT15) are key enzymes that catabolize thiopurines. Decreased or no‐function alleles in TPMT and NUDT15 are associated with reduced or no enzyme activity and predictive of pronounced adverse effects, including severe myelosuppression, that may occur among individuals treated with standard ...
Maud Maillard   +18 more
wiley   +1 more source

[Perioperative morbidity and mortality of cardiac surgeries at the Instituto Nacional Cardiovascular, Lima, Peru, during the year 2023]. [PDF]

open access: yesArch Peru Cardiol Cir Cardiovasc
Silva-Tejada H   +4 more
europepmc   +1 more source

National Identity Meaning and Attitudes Toward War, Peace, and the Future of Ukraine

open access: yesConflict Resolution Quarterly, EarlyView.
ABSTRACT The link between attitudes and social identity is complex, influencing perceptions, motivations, and actions. Social psychological research mainly focused on the role of attitude in identity formation, particularly in the contexts of social movements and collective action.
Karina V. Korostelina   +6 more
wiley   +1 more source

Purpose and Profit: Social and Environmental Marketing for Large Companies in Adverse Scenarios

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This qualitative study explored how large companies use social and environmental marketing to boost results in adverse scenarios, analyzing interviews with marketing managers and public documents. The findings reveal distinct strategies. To attract investors, environmental, social, and governance (ESG) communication is targeted at limited ...
Celso Jacubavicius   +4 more
wiley   +1 more source

[Classification and characterization of exposure among artisanal fishers to the oil spill in Pernambuco, Brazil]. [PDF]

open access: yesCad Saude Publica
Gonçalves JE   +5 more
europepmc   +1 more source

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