Results 111 to 120 of about 4,490 (182)

In vitro and in silico modelling of ROS1-positive non-small cell lung cancer reveals fusion-dependent tyrosine kinase inhibitor responses. [PDF]

Mol Oncol
Ul Haq F, Terrones M, Rodrigues Fortes F, Schepers A, Denis A, Deben C, Op de Beeck K, Van Camp G, Vandeweyer G.   +8 more
europepmc   +1 more source

Targeting Oncogenic Gene Fusions in Lung Cancer. [PDF]

Cancer J
Nie Y, Wilson FH.
europepmc   +1 more source

Development of PROTACs for targeted degradation of oncogenic TRK fusions. [PDF]

RSC Chem Biol
Kumar S, Jiang J, Donald-Paladino MS, Chen J, Gutierrez A, Federation AJ, Szulzewsky F, Holland EC, Ferguson FM, Nabet B.   +9 more
europepmc   +1 more source

Real-World Evidence for Oncology Patients With Rare <i>NTRK</i> Gene Fusions: Final Results From the German Multicenter Patient Cohort Study REALTRK. [PDF]

JCO Precis Oncol
Potthoff K, Lange S, Seufferlein T, Heinrich K, Claus R, Bleckmann A, Zaiss M, Vannier C, Grebhardt S, Koszinowski S, Hillebrand LE, Ringwald K, Kasenda B.   +12 more
europepmc   +1 more source

Repurposing ALK inhibitors as influenza and corona virus antivirals targeting lymphocyte tyrosine kinase (LTK). [PDF]

Virus Res
Tjärnhage E, Våtsveen TK, Raki M, Nemazee D, Farhan H, Munthe L, Grodeland G.   +6 more
europepmc   +1 more source

Minimal residual disease assessment through ctDNA facilitates tailored immunotherapy in MSI-high, NTRK1-fusion pancreatic adenocarcinoma. [PDF]

Oncologist
Rohlfing S, Vladimirova D, Berger S, Bochum S, Otmacic G, Weiß M, Sipos B, Biskup S, Klaumünzer M, Martens UM.   +9 more
europepmc   +1 more source

Modeling the Effects of Single Nucleotide Polymorphisms (SNPs) on the Structure and Function of the Human <i>RET</i> Gene: An In Silico Study. [PDF]

Hum Mutat
Anzoom N, Hossain MA, Hossain MT, Uddin MM, Khan M, Islam MS, Ansari SA, Rahman MH.   +7 more
europepmc   +1 more source

Late Onset of Entrectinib-Related ST Elevation in the Setting of Alcohol Intoxication in a Patient With Metastatic Non-small Cell Lung Cancer: A Case Report and Literature Review. [PDF]

Cureus
Xia C, Kosmider S.
europepmc   +1 more source

ETV6-NTRK3 as a resistance mechanism to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors: favorable response after combination of osimertinib and entrectinib: a case report and literature review. [PDF]

Front Pharmacol
Xie W, Luo H, Wang H, Shi G, Tang J, Ma L, Zhou J.   +6 more
europepmc   +1 more source

In silico Identification of Natural Compounds as Potential TrkA Inhibitors for Anticancer Drug Development. [PDF]

Iran J Pharm Res
Fadhil M, Al-Fahad D, Azam F, Asadi A.
europepmc   +1 more source