Results 101 to 110 of about 2,750,389 (295)

Quantum Theory of Irreversibility

open access: yes, 2005
A generalization of the Gibbs-von Neumann relative entropy is proposed based on the quantum BBGKY [Bogolyubov-Born-Green-Kirkwood-Yvon] hierarchy as the nonequilibrium entropy for an N-body system.
A. Pérez-Madrid   +14 more
core   +2 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Volume staging for arteriovenous malformation SRS treatment using VMAT

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Volume staging involves dividing the target volume into smaller parts and treating each part separately. In this study, the feasibility of volume‐staged stereotactic radiosurgery (VS‐SRS) on a linear accelerator using volumetric modulated arc therapy (VMAT) and a frameless patient positioning system is investigated.
Claudia Mendez, Ermias Gete
wiley   +1 more source

The Global Nature of the Arrow of Time and the Bohm-Reichenbach diagram [PDF]

open access: yesarXiv, 2000
The importance of the global nature of the arrow of time is shown. Classical Reichenbach diagram and quantum Bohm-Reichenbach diagram, for the universe are introduced. They are used to show the increase of entropy in closed systems, the global nature of the quantum measurement, and the relation among the different arrows of time.
arxiv  

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Comment on "Spontaneous Inflation and the Origin of the Arrow of Time" [PDF]

open access: yesarXiv, 2004
Recently, Carroll and Chen [hep-th/0410270] suggested a promising natural explanation of the thermodynamic arrow of time. However, we criticize their assertion that there exists a Cauchy hypersurface with a minimal entropy and argue that such a Cauchy hypersurface is not needed for an explanation of the arrow of time.
arxiv  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

The holographic space-time and black hole remnants as dark matter

open access: yesPhysics Letters B, 2022
The holographic space-time approach to inflation provides a well defined and self-contained framework to study the early universe. Based on a quasi-local quantum gravity theory generalizing string theory beyond AdS backgrounds, it addresses fundamental ...
Aurélien Barrau
doaj  

A compromised arrow of time [PDF]

open access: yesarXiv, 2000
The second law of thermodynamics - the usual statement of the arrow of time - has been called the most fundamental law of physics. It is thus difficult to conceive that a single dynamical system could contain subsystems, in significant mutual contact, possessing opposite thermodynamic arrows of time.
arxiv  

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

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