Results 71 to 80 of about 70,673 (206)

Algorithmic independence of initial condition and dynamical law in thermodynamics and causal inference

New Journal of Physics, 2016
We postulate a principle stating that the initial condition of a physical system is typically algorithmically independent of the dynamical law. We discuss the implications of this principle and argue that they link thermodynamics and causal inference. On
Dominik Janzing, Rafael Chaves, Bernhard Schölkopf   +2 more
doaj   +1 more source

Fisher's arrow of `time' in cosmological coherent phase space

, 1998
Fisher's arrow of `time' in a cosmological phase space defined as in quantum optics (i.e., whose points are coherent states) is introduced as follows. Assuming that the phase space evolution of the universe starts from an initial squeezed cosmological ...
B. ROY FRIEDEN, Frieden B. R., Gasperini M., Grishchuk L., Grishchuk L. P., H. C. ROSU, Plastino A. R., Rothman T., Winitzki S., Zel’dovich Ya. B.   +9 more
core   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source

Does time exist in quantum gravity?

Zagadnienia Filozoficzne w Nauce, 2015
Time is absolute in standard quantum theory and dynamical in general relativity. The combination of both theories into a theory of quantum gravity leads therefore to a “problem of time”.
Claus Kiefer
doaj  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Cancer biomarker discovery: the entropic hallmark. [PDF]

PLoS ONE, 2010
BACKGROUND: It is a commonly accepted belief that cancer cells modify their transcriptional state during the progression of the disease. We propose that the progression of cancer cells towards malignant phenotypes can be efficiently tracked using high ...
Regina Berretta, Pablo Moscato
doaj   +1 more source

Irreversibility as thermodynamic time

Open Physics, 2021
In Newtonian mechanics, time and space are perceived as absolute entities. In Einstein’s relativity theory, time is frame dependent. Time is also affected by gravitational field and as the field varies in space, time also varies throughout space.
Hwang Charles C.
doaj   +1 more source

Is Entropy Associated with Time's Arrow?

, 2017
We start with reviewing the origin of the idea that entropy and the Second Law are associated with the Arrow of Time. We then introduced a new definition of entropy based on Shannons Measure of Information, SMI. The SMI may be defined on any probability distribution, and therefore it is a very general concept.
openaire   +2 more sources

Entropy and the Idea of God(s): A Philosophical Approach to Religion as a Complex Adaptive System

Religions
While a universal definition of religion eludes the field of religious studies, it certainty seems that people are becoming differently religious rather than a-religious, especially since the latter half of the twentieth century.
Matthew Zaro Fisher
doaj   +1 more source