Results 81 to 90 of about 268,561 (292)

The thermodynamics of optical étendue

, 2008
The concept of ´etendue is applied to the propagation of luminescent radiation, and to the transformation of such radiation in absorbing and luminescent media.
Markvart, T.
core   +1 more source

Generation of entropy and forced convection of heat in a conduit partially filled with porous media- Local thermal non-equilibrium and exothermicity effects applied thermal engineering [PDF]

, 2016
The performance of a two-dimensional, axisymmetric channel with porous inserts attached to the walls is analyzed from the perspective of the first and second laws of thermodynamics.
Karimi, Nader, Peterson, G.P., Torabi, Mohsen, Zhang, Kaili   +3 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Analysis of Entropy Generation Rate in an Unsteady Porous Channel Flow with Navier Slip and Convective Cooling

Entropy, 2013
This study deals with the combined effects of Navier Slip, Convective cooling, variable viscosity, and suction/injection on the entropy generation rate in an unsteady flow of an incompressible viscous fluid flowing through a channel with permeable walls.
Oluwole Daniel Makinde, Tirivanhu Chinyoka   +1 more
doaj   +1 more source

Quantum random number generation for 1.25 GHz quantum key distribution systems

, 2015
Security proofs of quantum key distribution (QKD) systems usually assume that the users have access to source of perfect randomness. State-of-the-art QKD systems run at frequencies in the GHz range, requiring a sustained GHz rate of generation and ...
Houlmann, R., Lim, C. C. W., Martin, A., Sanguinetti, B., Zbinden, H.   +4 more
core   +2 more sources

Entropy generation analysis for the design improvement of a latent heat storage system [PDF]

, 2013
The aim of this work is to investigate design improvements of a shell-and-tube latent heat thermal energy storage unit using an approach based on the analysis of entropy generation.
Adriano Sciacovelli, Agyenim, Agyenim, Bejan, Bejan, Cabeza, Chiu, Choi, David MacPhee, De Groot, Elisa Guelpa, Erek, Erek, Ezan, Hirschfelder, Ismail, Ismail, Jegadheeswaran, Jegadheeswarana, Kaizawa, Kousksou, Lacroix, Mesalhy, Sari, Sciacovelli, Vittorio Verda, Voller, Zalba   +27 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Combined Effect of Buoyancy Force and Navier Slip on Entropy Generation in a Vertical Porous Channel

Entropy, 2012
In this paper, we investigate the combined effects of buoyancy force and Navier slip on the entropy generation rate in a vertical porous channel with wall suction/injection.
Oluwole Daniel Makinde, Adetayo Samuel Eegunjobi   +1 more
doaj   +1 more source

Homotopy study of magnetohydrodynamic mixed convection nanofluid multiple slip flow and heat transfer from a vertical cylinder with entropy generation [PDF]

, 2019
Stimulated by thermal optimization in magnetic materials process engineering, the present work investigates theoretically the entropy generation in mixed convection magnetohydrodynamic (MHD) flow of an electrically-conducting nanofluid from a vertical ...
Abolbashari, Andersson, Aziz, Aïboud, Bejan, Bejan, Buongiorno, Choi, Dhanai, Dhanai, Fang, Hatami, Heysiattalab, Ismael, Kuznetsov, Liao, Liao, Mabood, Mabood, Mahgoub, Malvandi, Nayfeh, Nazar, Noghrehabadi, Raftari, Rana, Rana, Rana, Rana, Rashad, Saidur, Sharma, Sheikholeslami, Sheikholeslami, Sheikholeslami, Sheikholeslami, Sheikholeslami, Sheikholeslami, Sheikholeslami, Sheikholeslami, Sheikholeslami, Sheikholeslami, Shukla, Sivasankaran, Trîmbiƫaş, Van Gorder, Wu, Yoshimura, Zaimi, Zheng, Zhu   +50 more
core   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source