Results 81 to 90 of about 224,912 (314)
Relative entropy methods for hyperbolic and diffusive limits [PDF]
, 2012 We review the relative entropy method in the context of hyperbolic and diffusive relaxation limits of entropy solutions for various hyperbolic models.
Tzavaras, Athanasios E. +1 more
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Calculation of the Entropy of a Copper Lattice Containing Random Mass Defects [PDF]
, 1974 Entropy of mixing for random mass defects is examined and equations for the phonon contribution are developed. The Green's function method used gives the entropy change due to the phonons at all temperatures, but for experimental comparison the high
Woodside, Robert
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Computing the entropy of user navigation in the web
, 2003 Navigation through the web, colloquially known as "surfing", is one of the main activities of users during web interaction. When users follow a navigation trail they often tend to get disoriented in terms of the goals of their original query and thus the
Levene, Mark, Loizou, George
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Methods to Calculate Entropy Generation
EntropyEntropy generation, formulated by combining the first and second laws of thermodynamics with an appropriate thermodynamic potential, emerges as the difference between a phenomenological entropy function and a reversible entropy function. The phenomenological entropy function is evaluated over an irreversible path through thermodynamic state space via ...
Jude A. Osara, Michael D. Bryant
openaire +4 more sources
Beyond Moments: Extending the Maximum Entropy Principle to Feature Distribution Constraints
, 2022 Art.650, 13 S.The maximum entropy principle introduced by Jaynes proposes that a data distribution should maximize the entropy subject to constraints imposed by the available knowledge.
Baggenstoss, P.M.
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source