Results 101 to 110 of about 153,546 (278)

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Negative mixing enthalpy approach for advanced multi-component alloys: a perspective for high strength yet ductile alloy development

Materials Research Letters
In high-entropy alloys (HEA), mixing entropy governs element distribution, while mixing enthalpy dictates interatomic interactions, influencing the formation of solid solutions or intermetallic compounds.
Jiaqi Meng, Xuefei Chen, Zibing An, Yi Liu, Yonghao Zhao, Hao Zhou, Xiaodong Han   +6 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Convective Mixing in Gas Giant Planets with Primordial Composition Gradients

The Astrophysical Journal
Linking atmospheric measurements to the bulk planetary composition and ultimately the planetary origin is a key objective in planetary science. In this work, we identify the cases in which the atmospheric composition represents the bulk composition.
Henrik Knierim, Ravit Helled
doaj   +1 more source

Mixing Property of Quantum Relative Entropy

, 2003
4 pages, Latex2e and ...
openaire   +2 more sources

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Thermally induced martensitic phase transformation in high-entropy alloys

Next Materials
High-entropy alloys have become an important topic to study in modern materials science due to extraordinary properties which are manipulatable by changing chemical composition and microstructure engineering.
Hamed Shahmir
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Elucidating the Role of the Mixing Entropy in Equilibrated Nanoconfined Reactions

Entropy
By introducing the concept of nanoreaction-based fluctuating mixing entropy, the challenge posed by the smallness of a closed molecular system is addressed through equilibrium statistical–mechanical averaging over fluctuating reaction extent.
Leonid Rubinovich, Micha Polak
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source