Results 101 to 110 of about 265,948 (327)
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Entropy Production Via Particle Production [PDF]
, 1995 I critically examine the notion of ``irreversibility,'' and discuss in what sense it applies to the spontaneous creation of particles in external fields. The investigation reveals that particle creation in very strong fields can only be described by a non-Markovian transport theory.
openaire +3 more sources
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Entropy Production-Based Energy Efficiency Optimization for Wireless Communication Systems
IEEE Open Journal of the Communications SocietyThe relationship between energy dissipation and information has been extensively studied in the emerging field of stochastic thermodynamics, where entropy production plays a core role in measuring the energy loss of irreversible processes. To analyze and
Litao Yan, Xiaohu Ge
doaj +1 more source
Fractal Structure and Entropy Production within the Central Nervous System
Entropy, 2014 Our goal is to explore the relationship between two traditionally unrelated concepts, fractal structure and entropy production, evaluating both within the central nervous system (CNS).
Andrew J. E. Seely +2 more
doaj +1 more source
Measuring the irreversibility of numerical schemes for reversible stochastic differential equations [PDF]
, 2012 . For a Markov process the detailed balance condition is equivalent to the time-reversibility of the process. For stochastic differential equations (SDE’s) time discretization numerical schemes usually destroy the property of time-reversibility.
Luc Rey-bellet +6 more
core +1 more source
Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
Entropy production for coarse-grained dynamics
New Journal of Physics, 2019 Systems out of equilibrium exhibit a net production of entropy. We study the dynamics of a stochastic system represented by a Master equation (ME) that can be modeled by a Fokker–Planck equation in a coarse-grained, mesoscopic description.
D M Busiello, J Hidalgo, A Maritan
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source