Results 101 to 110 of about 442,315 (312)
Extreme-value statistics of stochastic transport processes
New Journal of Physics, 2020 We derive exact expressions for the finite-time statistics of extrema (maximum and minimum) of the spatial displacement and the fluctuating entropy flow of biased random walks.
Alexandre Guillet +2 more
doaj +1 more source
EURASIP Journal on Advances in Signal Processing, 2021 To solve the problem of ergonomic evaluation of suit production system, a hybrid method of IAHP and gray entropy theory is proposed. Firstly, literature reviews for ergonomics evaluation tools and techniques are introduced.
Laihong Du, Hua Chen, Yadong Fang
doaj +1 more source
How Fast Does Information Leak out from a Black Hole?
, 1993 Hawking's radiance, even as computed without account of backreaction, departs from blackbody form due to the mode dependence of the barrier penetration factor. Thus the radiation is not the maximal entropy radiation for given energy.
A. A. Starobinsky +31 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Vacuum Structure and the Arrow of Time
, 2012 We find ourselves in an extended era of entropy production. Unlike most other observations, the arrow of time is usually regarded as a constraint on initial conditions. I argue, however, that it primarily constrains the vacuum structure of the theory.
A. Linde +4 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Entropy production from chaoticity in Yang-Mills field theory with use of the Husimi function [PDF]
, 2016 We investigate possible entropy production in Yang-Mills (YM) field theory by using a quantum distribution function called Husimi function fH(A,E,t) for YM field, which is given by a coarse graining of Wigner function and non-negative.
Hidekazu Tsukiji +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source