Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Quantum properties of a non-Gaussian state in the large-N approximation
We study the properties of a non-Gaussian density matrix for a O(N) scalar field in the context of the incomplete description picture. This is of relevance for studies of decoherence and entropy production in quantum field theory. In particular, we study
Gautier, F., Serreau, J.
core +3 more sources
Network Localization of Fatigue in Multiple Sclerosis
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo +12 more
wiley +1 more source
Mechanism of irreversible energy loss in impeller of contra-rotating axial fan
With the urgent need of energy saving and consumption reduction in today's world, the topic of increasing the energy conversion efficiency of ventilation fans has been attracted a lot of attentions, it has become a key issue in the field of ventilation ...
Yongping CHEN +6 more
doaj +1 more source
Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer +14 more
wiley +1 more source
A Kinetic Perspective on k - ϵ Turbulence Model and Corresponding Entropy Production
In this paper, we present an alternative derivation of the entropy production in turbulent flows, based on a formal analogy with the kinetic theory of rarefied gas.
Pietro Asinari +2 more
doaj +1 more source
ABSTRACT Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune‐mediated neuropathy featuring progressive weakness, sensory deficits, and areflexia. While corticosteroids, intravenous immunoglobulin, and plasmapheresis are effective first‐line immunotherapies, a subset of patients remains treatment‐refractory.
Xueyu Zhang +8 more
wiley +1 more source
A novel pumped storage system using centrifugal pumps to transfer water between reservoirs in coastal hydropower plants has significantly mitigated grid instability. However, frequent start–stop operations of large vertical centrifugal pumps, which serve
Qingzhao Pang +6 more
doaj +1 more source
Rethinking evolution, entropy and economics: A triadic conceptual framework for the maximum entropy principle as applied to the growth of knowledge [PDF]
Recently, the maximum entropy principle has been applied to explain the evolution of complex non-equilibrium systems, such as the Earth system. I argue that it can also be fruitfully deployed to reconsider the classical treatment of entropy in economics ...
Herrmann-Pillath, Carsten
core
Functional Connectivity Linked to Cognitive Recovery After Minor Stroke
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri +7 more
wiley +1 more source

