Results 161 to 170 of about 4,356,871 (306)
From CRISPR functional genomics to synthetic interventions: engineering antiviral strategies. [PDF]
Qiao W.
europepmc +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Prevalence and risk factors for AMS: A systematic review and meta-analysis. [PDF]
Liu X +7 more
europepmc +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Residence and insurance inequities in the timeliness of access to first-eye cataract surgery in Eastern China. [PDF]
Qin C, Zhu J, Yang T.
europepmc +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Clade C MERS-CoV camel strains vary in protease utilization during viral entry. [PDF]
Winstone H +5 more
europepmc +1 more source

