Results 241 to 250 of about 2,530,373 (308)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Integrin β3 α2,6-sialylation by the sialyltransferase ST6Gal1 promotes human cytomegalovirus entry into fibroblasts. [PDF]

Virulence
Pan T, Wang H, Guo L, Tang G, Zheng L.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Standardizing the Yamane flanged intrascleral haptic fixation: A framework for efficacy, complication mitigation, and reproducible training. [PDF]

World J Methodol
Usta Küçükbezirci G, Gürcan B, Patel N, Ramsey DJ, Alwreikat A.   +4 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Concomitant Production and Transfer of Hydrogen for Efficient <i>In Situ</i> Reduction of C-C and C-O Unsaturated Substrates by Pt/TiO₂ Photocatalyst in Ethanol. [PDF]

ACS Omega
Delaunay O, Denicourt-Nowicki A, Roucoux A.   +2 more
europepmc   +1 more source

Data-Entry Error in Meta-Analysis of Suicide Prevention in Children and Adolescents.

JAMA Pediatr
europepmc   +1 more source

Computerized Physician Order Entry and Pediatric Prescribing Errors: A Multicenter Database Study. [PDF]

Drug Healthc Patient Saf
Komargodski R, Youngster I, Ticho I, Masarwi M, Yeruham R, Shaharabani IL, Benis A, Moldaver I, Krupik D, Klein A, Hachmo Y, Kozer E.   +11 more
europepmc   +1 more source

Case Report: Electrode perforation with normal pacemaker parameters leading to hemorrhagic shock: a rare case report of the "penetration-exit-re-entry" phenomenon. [PDF]

Front Med (Lausanne)
Qin Z, Yang J, Luo L, Chen S, Yang F.
europepmc   +1 more source

Totally Extraperitoneal Endoscope-assisted Deep Inferior Epigastric Perforator Flap Harvest Using an Optical Trocar. [PDF]

Plast Reconstr Surg Glob Open
Katsuragi R, Hayashi K, Abe N, Yamamoto Y, Okiyama M, Zaha H, Satake T.   +6 more
europepmc   +1 more source