Results 21 to 30 of about 14,872 (259)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Warum gibt es in Deutschland ein Problem in der ambulanten Versorgung?

open access: yesMonitor Versorgungsforschung
Trotz steigender Arztzahlen und Arztdichte im ambulanten Bereich hat sich in Deutschland in den vergangenen Jahren ein Versorgungsproblem entwickelt. Offensichtlich wird es für Patienten immer schwerer, einen Termin bei einem Facharzt zu bekommen oder ...
Dr. med. Manfred Eissler
doaj   +1 more source

Videotest zur Erfassung «adaptiver Lehrkompetenz»

open access: yesBeiträge zur Lehrerinnen- und Lehrerbildung, 2005
Mit dem Ziel, adaptive Lehrkompetenz von Lehrpersonen möglichst unterrichtsnah aber dennoch standardisiert zu erfassen, wurde im Rahmen des National-fonds-Projekts «Adaptive Lehrkompetenz» ein Videotest entwickelt.
Sonja Bischoff   +2 more
doaj   +1 more source

Light‐Induced Field‐Tunneling Synapses in Solution‐Processed Van Der Waals Heterostructures for Scalable, Retina‐Inspired Optical Sensing

open access: yesAdvanced Functional Materials, EarlyView.
A scalable, solution‐processed WSe2/ZrO2‐x van der Waals heterostructure realizes a light‐induced field‐tunneling synapse (LIFTS) that activates exclusively under bright illumination, emulating the photopic adaptation of the human retina at the device level.
Kijeong Nam   +10 more
wiley   +1 more source

Flächensparen zwischen Anspruch und Wirklichkeit. Zur Rolle von Akteuren und Steuerungsinstrumenten in Dorferneuerungsprozessen

open access: yesRaumforschung und Raumordnung, 2018
Using the example of the Bavarian Village Renewal Programme, the article investigates which steps and instruments of the village renewal process are capable of steering actors towards a reduction of land take.
Anne Ritzinger
doaj   +1 more source

A Lightweight, 3D‐Printable, Low‐Cost, “One‐Click” Dorsal Skin Window for High‐Quality Long‐Term Multimodal Subcutaneous Tumor Imaging

open access: yesAdvanced Healthcare Materials, EarlyView.
An innovative, lightweight 3D‐printed skinfold chamber system is presented for long‐term intravital imaging. This affordable, biocompatible platform simplifies surgical implantation and allows high‐resolution, multimodal visualization of the tumor microenvironment for up to four weeks.
Iván Cortés Domínguez   +9 more
wiley   +1 more source

Charakterisierung zweier neuer antioxidativer Tetrahydroxyxanthone in Hypericum-Samen und rasterelektronenmikroskopische Untersuchung der Testa

open access: yesJulius-Kühn-Archiv, 2018
Hypericum seeds have recently been identified as a natural source of different xanthone derivatives. Two main constituents, the tetrahydroxyxanthones THX-1 and -2, were identified in methanolic extracts of H. perforatum and H.
Lorenz, Peter   +7 more
doaj   +1 more source

Patterned ELR‐Gelatin Hydrogels Enable Rapid Endothelial Monolayer Formation via Bioactive Matrix Chemistry and Surface Topography

open access: yesAdvanced Healthcare Materials, EarlyView.
Micro‐ and nano‐patterned elastin‐like recombinamer (ELR) hydrogels integrate bioactive matrix chemistry with defined surface topography. The combined cues promote rapid endothelial cell capture, alignment, and monolayer formation on soft substrates.
Jagoda Litowczenko   +8 more
wiley   +1 more source

Artificial Intelligence‐Assisted Workflow for Transmission Electron Microscopy: From Data Analysis Automation to Materials Knowledge Unveiling

open access: yesAdvanced Materials, EarlyView.
AI‐Assisted Workflow for (Scanning) Transmission Electron Microscopy: From Data Analysis Automation to Materials Knowledge Unveiling. Abstract (Scanning) transmission electron microscopy ((S)TEM) has significantly advanced materials science but faces challenges in correlating precise atomic structure information with the functional properties of ...
Marc Botifoll   +19 more
wiley   +1 more source

Home - About - Disclaimer - Privacy