Results 21 to 30 of about 14,736 (258)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Statistische Analysen von Semantic Entities aus Metadaten- und Volltextbeständen von German Medical Science

open access: yesGMS Medizin – Bibliothek – Information, 2017
This paper analyzes the information content of metadata and full texts in German Medical Science (GMS) articles in English language. The object of the study is to compare semantic entities that are used to enrich GMS metadata (titles and abstracts) and ...
Grün, Stefan, Poley, Christoph
doaj   +1 more source

Enhancing Bubble Removal in Geometry‐Optimized Electrodes

open access: yesAdvanced Engineering Materials, EarlyView.
3D‐printed lattice electrodes outperform stochastic foams in alkaline water electrolysis despite 20%–25% lower surface area. Straight flow channels generate Venturi‐like bubble entrainment, suppressing gas accumulation that renders foam interiors electrochemically inactive.
Florian Wiesner   +5 more
wiley   +1 more source

Warum gibt es in Deutschland ein Problem in der ambulanten Versorgung?

open access: yesMonitor Versorgungsforschung
Trotz steigender Arztzahlen und Arztdichte im ambulanten Bereich hat sich in Deutschland in den vergangenen Jahren ein Versorgungsproblem entwickelt. Offensichtlich wird es für Patienten immer schwerer, einen Termin bei einem Facharzt zu bekommen oder ...
Dr. med. Manfred Eissler
doaj   +1 more source

Videotest zur Erfassung «adaptiver Lehrkompetenz»

open access: yesBeiträge zur Lehrerinnen- und Lehrerbildung, 2005
Mit dem Ziel, adaptive Lehrkompetenz von Lehrpersonen möglichst unterrichtsnah aber dennoch standardisiert zu erfassen, wurde im Rahmen des National-fonds-Projekts «Adaptive Lehrkompetenz» ein Videotest entwickelt.
Sonja Bischoff   +2 more
doaj   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

open access: yesAdvanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano   +11 more
wiley   +1 more source

Flächensparen zwischen Anspruch und Wirklichkeit. Zur Rolle von Akteuren und Steuerungsinstrumenten in Dorferneuerungsprozessen

open access: yesRaumforschung und Raumordnung, 2018
Using the example of the Bavarian Village Renewal Programme, the article investigates which steps and instruments of the village renewal process are capable of steering actors towards a reduction of land take.
Anne Ritzinger
doaj   +1 more source

Artificial Intelligence‐Assisted Workflow for Transmission Electron Microscopy: From Data Analysis Automation to Materials Knowledge Unveiling

open access: yesAdvanced Materials, EarlyView.
AI‐Assisted Workflow for (Scanning) Transmission Electron Microscopy: From Data Analysis Automation to Materials Knowledge Unveiling. Abstract (Scanning) transmission electron microscopy ((S)TEM) has significantly advanced materials science but faces challenges in correlating precise atomic structure information with the functional properties of ...
Marc Botifoll   +19 more
wiley   +1 more source

Charakterisierung zweier neuer antioxidativer Tetrahydroxyxanthone in Hypericum-Samen und rasterelektronenmikroskopische Untersuchung der Testa

open access: yesJulius-Kühn-Archiv, 2018
Hypericum seeds have recently been identified as a natural source of different xanthone derivatives. Two main constituents, the tetrahydroxyxanthones THX-1 and -2, were identified in methanolic extracts of H. perforatum and H.
Lorenz, Peter   +7 more
doaj   +1 more source

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