Results 191 to 200 of about 391,750 (316)
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
IQ, an Uninvited Guest in the Field of Learning?: Correlation Study of Comprehensive Learning Test. [PDF]
Cha MC+4 more
europepmc +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Long-term Effects of Local Area New Deal Work Relief in Childhood on Late-Life Depression. [PDF]
Modrek S, Rehkopf DH.
europepmc +1 more source
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Intestinal bacteria translocation promotes β-cell dysfunction in DIO mice. [PDF]
Yu XF+9 more
europepmc +1 more source
The Presumptive Enumeration of Lactose Negative as well as Lactose Positive Enterobacteriaceae in Foods [PDF]
D. À. A. Mossel
openalex +1 more source