Results 71 to 80 of about 3,723,814 (311)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Materials Research Express, 2020 A thermoresponsive hydrogel that was composed of 2-hydroxy-3-isopropoxypropyl starch (HIPS) and alginate was synthesized via cross-linking with hybrid crosslinkers including ethylene glycol diglycidyl ether (EDGE) and calcium chloride (CaCl _2 ...
Mingyun Dai +5 more
doaj +1 more source
High voltage pulse generator [PDF]
, 1969 Generator has an improved circuit for generating a controllable, high voltage spark having a constant known energy output. It can be used for testing the flash and ignition characteristics of nonmetallic materials in a controlled gas ...
Pippen, D. L.
core +1 more source
Sensor node localisation using a stereo camera rig [PDF]
, 2007 In this paper, we use stereo vision processing techniques to detect and localise sensors used for monitoring simulated environmental events within an experimental sensor network testbed.
Beirne, Stephen +7 more
core +2 more sources
Autonomous vs. controlling educational environments [PDF]
Journal of Process Management. New Technologies, 2019 Active and motivated students are much desired in the educational context. Learning how to lead the students to find intrinsic motivation for schoolwork, help them self-regulate their learning and feel autonomous in the learning process is an important task of every educator.
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The Superconductor-Insulator Transition in a Tunable Dissipative Environment
, 1997 We study the influence of a tunable dissipative environment on the dynamics of Josephson junction arrays near the superconductor-insulator transition. The experimental realization of the environment is a two dimensional electron gas coupled capacitively ...
A. F. Hebard +21 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source