Results 121 to 130 of about 3,580,446 (245)

Tumor morphology on CT radiomics is largely driven by the local anatomical environment, not the primary tumor type. [PDF]

Eur Radiol Exp
Rostami S, Guérendel C, Soliman M, Stutterheim HW, Maxouri O, Rodríguez Sánchez DI, Ursprung S, Boveradze N, Agrotis G, Chupetlovska K, Castagnoli F, Landolfi F, Hong EK, Pizzi AD, Gennaro N, Abdelatty MA, Jutidamrongphan W, Petrychenko L, Matkulcik P, Salgado-Parente A, Arico FM, Benson S, Snaebjornsson P, Bodalal Z, Beets-Tan RGH.   +24 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Fock state probability changes in open quantum systems. [PDF]

Eur Phys J C Part Fields
Burrage C, Käding C.
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Road traffic noise affects annoyance during urban built and forest walks, but not repetitive negative thinking or connectedness with non-human nature: A randomized controlled trial. [PDF]

PLoS One
Schaupp J, Wunderli JM, Schäffer B, Hediger K, Bauer N.   +4 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Erratum: Global population structure of Shiga toxin-producing <i>Escherichia coli</i> O103:H2 and the variation in their major virulence factor-encoding genetic elements. [PDF]

Microb Genom
Taniguchi I, Morimoto Y, Kimura Y, Seto J, Kawai Y, Kitahashi T, Aoki J, Terai K, Furuta T, Wakabayashi Y, Tanabe S, Hamasaki M, Abe Y, Sasaki M, Narimatsu H, Yokoyama E, Iyoda S, Hayashi T, Nakamura K.   +18 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Multi-trait and multi-environment genomic prediction enhances yield components improvement in durum wheat. [PDF]

Front Plant Sci
Puglisi D, Crossa J, Cuevas J, Fania F, Vitale P, De Vita P.   +5 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source