Results 121 to 130 of about 7,653,177 (313)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Erratum to: Genes and Environment, Vol. 39
Genes and Environment, 2017 Genes and Environment
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Global environment outlook GEO-4: Environment for development
The Global Environment Outlook: environment for development (GEO-4) report is published in what may prove to be a remarkable year – a year when humanity faced up to the scale and pace of environmental degradation with a new sense of realism and honesty ...
United Nations Environment Programme
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Coastal habitats and sea level rise in Finland — vulnerability and adaptation
Publisher Copyright: © 2025, Finish Environment Institute. All rights reserved.Coastal meadows and sandy beaches in the Gulf of Finland are important habitats for a wide variety of species, but they are under threat from rising sea levels. In this study,
Heilala, Tomi +4 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Nurse Moral Distress and Ethical Work Environment
, 2005 This study examined the relationship between moral distress intensity, moral distress frequency and the ethical work environment, and explored the relationship of demographic characteristics to moral distress intensity and frequency.
Mary Jacobs +7 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Africa: Atlas of Our Changing Environment [PDF]
, 2008 This comprehensive atlas provides data, satellite imagery, and analysis of the environmental conditions and issues relevant to each African country, and several surrounding island nations.
United Nations Environment Programme
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