Results 161 to 170 of about 9,656,167 (251)

How experience shapes individuality. [PDF]

Elife
Hassan BA.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Perceived Work Environment, Professional Identity, and Dispositional Hope Among Nurse Interns: A Cross-Sectional Study. [PDF]

Healthcare (Basel)
Khalifa MAEG, Ibrahim RK, Hendy A, Alqarawi N, Badran FMM, Ali EHM, Ebraheem SMA.   +6 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Association between breakfast frequency, community space environment, and psychological symptoms: a cross-sectional study of Chinese adolescents. [PDF]

Front Psychol
Bai X, Bi C, Dong J, Sun J, Yang Q, Sun T.   +5 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Comprehensive security is founded on a good state of the environment

Climate change, biodiversity loss and the crossing of tipping points in the Earth System are among the most serious security risks in the coming decades. A deteriorating environment weakens people’s living conditions, acts as a driver of conflict, or may
Sojamo, Suvi, Ahopelto, Lauri, Kopsakangas-Savolainen, Maria, Pihlainen, Sampo, Storsjö, Isabell, Kivimaa, Paula, Munck af Rosenschöld, Johan, Vuori, Kari-Matti, Faehnle, Maija, Sivonen, Marja Helena, Mustajoki, Jyri   +10 more
core  

Preschool Environment and 24-h Behaviour Movement in Uruguayan Early Childhood: A Compositional Data Analysis. [PDF]

Child Care Health Dev
Fernandez-Gimenez S, Martins CL, Pintos-Toledo E, Souza-Marabotto F, Brazo-Sayavera J.   +4 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Learning and Using Different Task Rule Updating Strategies Require Extensive Practice. [PDF]

Cogn Sci
Xu S, Wen T, Egner T, Verguts T, Braem S.   +4 more
europepmc   +1 more source