Results 191 to 200 of about 10,830,821 (340)

Using fine‐scale spatial genetics of Norway rats to improve control efforts and reduce leptospirosis risk in urban slum environments [PDF]

, 2016
Jonathan Richardson, Mary K. Burak, Christian Hernandez, James M. Shirvell, Carol Mariani, Ticiana S. A. Carvalho‐Pereira, Arsinoê Cristina Pertile, Jesús Alonso Panti–May, Gabriel Pedra, Soledad Serrano, J. E. Taylor, Mayara Carvalho, Gorete Rodrigues, Federico Costa, James E. Childs, Albert I. Ko, Adalgisa Caccone   +16 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The Correlation Between Stress of Conscience and Burnout Among Health Care Personnel at an Acute Care Hospital in Southern Sweden: A Cross-Sectional Study. [PDF]

Scand J Caring Sci
Ekstrand M, Ekwall A, Porter S.
europepmc   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Effects of living environment quality on cultural heritage responsibility behaviors of residents in traditional villages: a case study from Hangzhou, China. [PDF]

Front Psychol
Jin M, Cao J, Zhao H, Li Z.
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

The longitudinal effect of perceived person-environment fit on academic trajectories and the mediating role of self-concepts and expectations of success. [PDF]

Eur J Psychol Educ
Ramseier L, Neuenschwander MP.
europepmc   +1 more source

Study on the Effect of Local Heating Devices on Human Thermal Comfort in Low-Temperature Built Environment [PDF]

Yalong Yang, Nana Shi, Rui Zhang, Hanxiang Zhou, Lei Ding, Jiamin Tao, Nan Zhang, Bin Cao   +7 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Impact of Virtual Reality-Based Rehabilitation on Postoperative Outcomes Following Total Hip Arthroplasty: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Zahed M, Elmesalmi M, Azaz R, Elkilany A, Elnaggar N, Ahmed F, El Menawy Z, Ramadan N, Adel M, Elhady MM.   +9 more
europepmc   +1 more source