Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effects of living environment quality on cultural heritage responsibility behaviors of residents in traditional villages: a case study from Hangzhou, China. [PDF]
Jin M, Cao J, Zhao H, Li Z.
europepmc +1 more source
Predicted MOND velocity dispersions for a catalog of ultra-diffuse galaxies in group environments [PDF]
Oliver Müller +2 more
openalex +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Effects of Workplace Violence on Emergency Nurses' Health: A Mediating and Moderating Role of Occupational Stress and the Work Environment. [PDF]
Chen X +5 more
europepmc +1 more source
Learning Design: Creating Powerful Learning Environments for Self-Regulation Skills [PDF]
Erik De Corte
openalex +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Comprehensive review on environmental pollution caused by 6PPD-quinone and remediation strategies. [PDF]
Sivalingam S +4 more
europepmc +1 more source

