Results 51 to 60 of about 3,674,725 (306)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
International Journal of Health Geographics, 2017 Background Local policy makers increasingly need information on health-related indicators at smaller geographic levels like districts or neighbourhoods.
Jan van de Kassteele +4 more
doaj +1 more source
From catering organisations to environmental and health related public catering systems [PDF]
, 2009 Based on the political legitimacy for healthy food and environment by the citizens, the traditional public catering is suggested to be conceptualised as a public catering system.
Mikkola, Minna
core
Antimicrobials in agriculture: reducing their use while limiting health and socioeconomic risks in the countries of the South [PDF]
, 2017 The widespread use of antimicrobials in agriculture is increasing, driven by growth in intensive livestock production and demand for animal products. This is creating a serious problem of antimicrobial resistance: bacteria are developing antimicrobial ...
Ducrot, Christian, Roger, François
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Environmental Sciences Europe, 2023 Background Lately scientific and societal concern has emerged about persistent (P), mobile (M) and toxic (T) chemicals. Such chemicals, like some polyfluoroalkyl acids (PFAAs), are of concern due to their high mobility and persistence in aquatic ...
Julia Hartmann +3 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Review of long-term immunogenicity following HPV vaccination: Gaps in current knowledge
Human Vaccines & Immunotherapeutics, 2022 The licensed HPV vaccines are highly efficacious and induce high levels of neutralizing antibody levels, the assumed mediators of protection. However, a correlate of protection against HPV is lacking, and the evidence is still limited as to long-term ...
J. Hoes +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Expert Review of Vaccines, 2017 Introduction: Many economic evaluations of HPV vaccination have been published, but most have focused on the prevention of cervical disease as a primary health outcome.
Anita W. M. Suijkerbuijk +6 more
doaj +1 more source