Results 41 to 50 of about 1,700,007 (268)
Preventive Care in Nursing and Midwifery JournalWe are writing this letter to highlight a critical and often overlooked issue in psychiatric care: the neglect of therapeutic architectural design as a fundamental component of patient recovery and safety.
Elham Amiri +4 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Impact of Intermediate Care Unit Architecture on Noise, Light, and Delirium Incidence
Noise and HealthObjective: To evaluate the effect of a newly constructed intermediate care unit (IMCU) on noise levels, lighting conditions, and delirium incidence.
Noel Schuerch +3 more
doaj +1 more source
Fire Behaviour of Insulation Panels Commonly Used in High-Rise Buildings
Fire, 2022 The energy efficiency of buildings drives the replacement of traditional construction materials with lightweight insulating materials. However, energy-efficient but combustible insulation might contribute to the building’s fire load.
Md Delwar Hossain +7 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
TechnologiesThe widespread availability of artificial intelligence (AI) tools has facilitated the development of complex, high-performance applications across a broad range of domains.
Marius Cristian Luculescu +2 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Facades for Achieving Visual Comfort: High Performance Computing
Environmental Science and Sustainable Development, 2019 Within the last few decades, many digital technologies have been integrated to the field of architecture. This in turn has developed a number of architectural trends based on these revolutionary changes.
Fatima Belok +3 more
doaj +1 more source