Results 151 to 160 of about 173,357 (309)

Microbiology of the Built Environment: Applying Our Knowledge for Healthy Indoor Spaces. [PDF]

open access: yesEnviron Sci Technol
Dannemiller KC   +4 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Payments for Environmental Services

open access: yes, 2007
Metadata only recordThe concept of Payments for Ecosystem Services (PES) seeks to create positive economic incentives to change human behaviour in ways that increase or maintain environmental services such as watershed protection, the sequestration of ...
Institute for Development Studies
core  

Strain-level analyses of public sequencing data to characterize <i>Escherichia coli</i> strain sharing between children and chickens in Mozambique. [PDF]

open access: yesOne Health
Olson N   +13 more
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Feature Story: U of R Wins Paragon Award for Environmental Excellence

open access: yes, 2013
At a gala dinner on April 5, the University of Regina was awarded the 2013 Regina & District Chamber of Commerce Paragon Award for Environmental Excellence.
External Relations, University of Regina
core  

Environmental and Social Drivers of Hidradenitis Suppurativa. [PDF]

open access: yesJAMA Dermatol
Baker NM   +13 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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