Results 131 to 140 of about 21,977,854 (330)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The potential of RIVPACS for predicting the effects of environmental change [PDF]

open access: yes, 2000
RIVPACS has been used successfully for biological assessment of river water quality but its potential in forecasting the effects of environmental change has not been investigated.
Armitage, P.D.
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Aerosols Shape the Vertical Structure of Convective Overshooting in Southeast Asia Through Microphysical Processes

open access: yesGeophysical Research Letters
Convective overshooting significantly influences atmospheric material and energy cycles and can cause severe social impacts; nevertheless, aerosol effects on its microphysical structure and associated extreme weather remain unclear. Using a more accurate
Nan Sun   +4 more
doaj   +1 more source

Environmental Conservation and Environmental Change

open access: yes, 2021
Abstract Chapter 1 introduces the content and structure of the book. It identifies the main characteristics of the Hotelling approach to conservation, and the nature of the conservation problems it can address. It summarizes the evidence for large-scale, systematic changes in biodiversity and ecological functioning across biomes.
openaire   +1 more source

Environmental Change and Hedonic Cost Functions for Automobiles [PDF]

open access: yes
This paper focuses on how changes in the economic and regulatory environment have affected production costs and product characteristics in the automobile industry. We estimate cost functions characteristics.
Ariel Pakes, Samuel Kortum, Steven Berry
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Environmental and Landscape Changes

open access: yes, 2015
Climate changes in western Sorkapp Land mirror global fluctuations. The Little Ice Age ended with a cold period in the 1890s. A warm contemporary period began in the early twentieth century. Afterwards, secondary cold and warm climate fluctuations occurred. The most recent fluctuation, since the 1980s, shows a significant warming trend. The mean annual
Ziaja, Wiesław   +6 more
openaire   +2 more sources

Technological Change and the Environment [PDF]

open access: yes
Environmental policy discussions increasingly focus on issues related to technological change. This is partly because the environmental consequences of social activity are frequently affected by the rate and direction of technological change, and partly ...
Jaffe, Adam   +2 more
core  

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