Results 121 to 130 of about 1,175,976 (304)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Life Cycle Assessment (LCA) Comparing Disinfection Options for Drinking Water Treatment [PDF]
, 2018 Drinking water treatment is essential to obtain a healthy source of water that can be distributed throughout a community. There are various methods to disinfect water, and all have trade-offs regarding public health and the environment.
Hidrovo, Alexandria
core +1 more source
Investigation of gold nanorods as a sensing material in plasmonic sensor for triclopyr butotyl detection [PDF]
, 2020 Gold nanorods (GNRs) have a unique optical property of metal nanoparticles (MNPs) due to the localised surface plasmon resonance (LSPR) effect, which depends on the size, shape and dielectric property of the surrounding medium.
Md Shah, Nur Zehan An’nisa
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
New strategies and advancements in the synthesis of metal organic frameworks for PAHs removal
iScienceSummary: Metal-organic frameworks (MOFs), a porous polymer having organic struts enclosed with clusters of metal ions, have shown an advantageous pathway for environmental remediation.
Cong Thanh Nguyen +3 more
doaj +1 more source
Solidification/stabilisation of soil contaminated with metal: a review [PDF]
, 2008 Solidification/stabilisation (S/S) is generically defined as a chemical and physical alteration technique of reducing the mobility as well as solubility of contaminants in wastes in order to convert them into chemically inert form.
Goh, B.M., Yin, C-Y
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Checkpoint blockade and the stem‐like T cell trade‐off
Molecular Oncology, EarlyView.Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source