Results 51 to 60 of about 13,917,202 (306)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Research progress in materials-oriented chemical engineering in China

, 2019
Materials-oriented chemical engineering involves the intersection of materials science and chemical engineering. Development of materials-oriented chemical engineering not only contributes to material research and industrialization techniques but also ...
Li, Chunzhong, Zhang, Qiang, Wang, Jiexin, Han, Yongsheng, Fan, Yiqun, Jiang, Hao   +5 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Green chemical engineering in China

, 2019
In China, the rapid development greatly greatly promotes the national economic power and living standard but also inevitably brings a series of environmental problems.
Lou, Hongming, Zhang, Xiangping, Ren, Qilong, Qiu, Xueqing, Bai, Yinge, Ali, Mohammad Chand, Zhang, Suojiang, Liu, Changjun, Xie, Yuanbang, Gao, Hongshuai, Zhou, Xintong, Xu, Baohua   +11 more
core   +1 more source

Novel design methods for conventional oil-water separators

Heliyon, 2019
The regulatory effluent oil limit which is the allowable quantity of hydrocarbons in industrial and stormwater effluents varies from one country to another.
William E. Odiete, Jonah C. Agunwamba
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Controllable preparation and performance of bio-based poly(lactic acid-iminodiacetic acid) as sustained-release Pb2+ chelating agent

iScience, 2021
Summary: The bio-based lactic acid (LA) and the common metal ion chelating agent iminodiacetic acid (IDA) are used to design and prepare a polymeric sustained-release Pb2+ chelating agent by a brief one-step reaction.
Jian-Yun Lin, Xi-Ying Cao, Ying Xiao, Jin-Xin Wang, Shi-He Luo, Li-Ting Yang, Yong-Gan Fang, Zhao-Yang Wang   +7 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Occurrence of a wide range of antibiotics, estrogenic hormones, and UV-filters in engineered and natural systems: Development of analytical methods and investigation of ecological effects

, 2017
Anthropogenic chemicals like pharmaceuticals, hormones, and personal care products have been widely used for decades and trace amounts of these compounds have been detected in different environmental compartments partially as traditional municipal ...
He, KeHe, Ke
core   +1 more source