Results 111 to 120 of about 7,263,430 (296)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Graduate Study in Chemistry, The University of Texas at Austin, circa 1977

open access: yes, 1977
Table of Contents: Foreword (p. 3) -- The University (p. 4) -- The Austin Community (p. 6) -- Texas and Central Texas (p. 10) -- The Chemistry Department (p. 14) -- Research Specializations (p. 20-81) -- Analytical Chemistry (p.
Chemistry Department
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Department of Chemistry Newsletter (Spring 1981, No. 4)

open access: yes, 1981
The newsletter of the Department of Chemistry, published once or twice a year, highlights people, events, and facilities. Content includes brief articles on new faculty hires, faculty and staff retirements, obituaries, major facilities and equipment ...
Department of Chemistry
core   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Research on the mechanism for removal of soluble BOD5 in clarifier systems. First pilot scale trial. Project 3216, EPA Ref. No. R 803-119-01, report three: a progress report to members of the Institute of Paper Chemistry

open access: yes, 1975
"EPA Ref. No. R 803-119-01.""August 18, 1975.""The Institute of Paper Chemistry, George A. Dubey, Averill J. Wiley, and Hardev S. Dugal, director, Division of Industrial and Environmental Systems.
Dugal, Hardev S.   +2 more
core  

Developing a survey instrument to evaluate tertiary chemistry students' attitudes and learning experiences [PDF]

open access: yes, 2001
New Zealand tertiary institutions, like others worldwide, have experienced a decline in science and chemistry enrolments in recent times as students seek other career paths that they perceive to be more lucrative.
Dalgety, Jacinta   +3 more
core  

Graduate Study in Chemistry, The University of Texas at Austin, 1979

open access: yes, 1979
Table of Contents: Foreword (p. 3) -- The University (p. 4) -- The City (p. 6) -- The Region (p. 7) -- The Department (p. 8) -- Research Specializations (p. 10-67) -- Analytical Chemistry (p. 11) -- Biochemistry (p. 16) -- Inorganic Chemistry (p.
Chemistry Department
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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