Results 141 to 150 of about 1,418,768 (341)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Leveraging Interfacial Electric Field for Smart Modulation of Electrode Surface in Nitrate to Ammonia Conversion

Advanced Science
The efficiency of nitrate reduction reaction (NO3RR) at low nitrate concentration is predominantly hindered by the poor affinity of nitrate ions and competitive hydrogen evolution reaction (HER), particularly in neutral and acidic media.
Kouer Zhang, Yifan Xu, Fatang Liu, Qing Wang, Xiaohong Zou, Mingcong Tang, Michael K.H. Leung, Zhimin Ao, Xunhua Zhao, Xiao Zhang, Liang An   +10 more
doaj   +1 more source

Environmental chemistry and ecotoxicology: in greater demand than ever. [PDF]

Environ Sci Eur, 2017
Scheringer M.
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Introduction to Environmental Chemistry of the Arctic: An Introductory, Lab-Based Course Offered Both Face-to-Face and by Distance. [PDF]

ACS Symp Ser Am Chem Soc, 2018
Guerard JJ, Hayes SM.
europepmc   +1 more source

Automated Clean Chemistry for Bulk Analysis of Environmental Swipe Samples – Final Report

, 2018
Brian W. Ticknor, Shalina C. Metzger, Eddy H. McBay, Cole R. Hexel, Kayron T. Rogers, Debra A. Bostick   +5 more
openalex   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Catalytic Hydrolysis of Perfluorinated Compounds in a Yolk–Shell Micro‐Reactor

Advanced Science
Perfluorinated compounds (PFCs) are emerging environmental pollutants characterized by their extreme stability and resistance to degradation. Among them, tetrafluoromethane (CF4) is the simplest and most abundant PFC in the atmosphere.
Jialin Zheng, Xiaojian Wang, Xin Zi, Hang Zhang, Heping Chen, Evangelina Pensa, Kang Liu, Junwei Fu, Zhang Lin, Liyuan Chai, Emiliano Cortés, Min Liu   +11 more
doaj   +1 more source

Progress in ecotoxicology, environmental chemistry and ecology. [PDF]

Environ Sci Eur, 2014
Sures B, Ruchter N, Zimmermann S, Eisinger M, Hollert H.   +4 more
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source